New Antioxidant Flavonoids from the Aerial Parts of Secamone Afzelii
Journal Title: Journal of Antioxidant Activity - Year 2015, Vol 1, Issue 2
Abstract
A bioassay-guided fractionation of petroleum ether, EtOAc and n-BuOH soluble parts of the 80% hydromethanol extract was performed to investigate the antioxidant activity of Secamoneafzeliiaerial parts using DPPH free radical scavenging assay. The results revealed that EtOAc and n-BuOH soluble parts have moderate to good DPPH radical scavenging activity (EC50 = 139.3 and 30.5 μg/mL, respectively). Therefore, from the most active fractions of EtOAc and n-BuOH soluble parts were isolated two new flavonoid diglycosides quercetin-3-O-β-d-apiofuranosyl-(1→2)-α-l-rhamnopyranoside and genkwanin-8-C-β-d-apiofuranosyl-(1→2)-β-d-glucopyranoside in addition to nine known compounds (2-10). Their structures were elucidated on the basis of spectroscopic data including 1D- and 2D-NMR and ESI-MS. The ability of the isolated compounds to scavenge the DPPH was evaluated. The new compound 1, quercitrin (3) and rutin (6) have antioxidant potential with EC50 values ranging from 8.4 to 13.6 µg/mL, compared to the standard ascorbic acid (EC50 7.4 µg/mL).
Authors and Affiliations
Abdulmagid Alabdul Magid, Yao-Kouassi Philomène Akoua, Diane Patricia Apie Gossan, Claire Mairot, Laurence Voutquenne-Nazabadioko
Keywords
Related Articles
- EP ID EP426367
- DOI 10.14302/issn.2471-2140.jaa-15-887
- Views 175
- Downloads 0
The Antioxidant and Hepatoprotective Activities of Two Tea Polysaccharides
In the present study, we investigated the chemical compositions, in vitro antioxidant and in vivo hepatoprotective activities of two tea polysaccharides (TPS), which were extracted from two different tea cultivars, Yings...
Antioxidant Protection of Donor Packed Red Blood Cells using Mexidol
The current research shows the possibility of long-term conservation of the erythrocytes an-tioxidant activity in the process of donor packed red blood cells while introducing mexidol to the hemoconservant glugicir compo...
Methionine and Antioxidant Potential
Methionine (Met) is a nutritionally essential amino acid and has been widely demonstrated to improve cellular oxidative balance and mediate oxidative stress. Met targets reactive oxygen species (ROS) directly by being ox...
Some Aspects of Regulatory Criteria for Metal-ligand Homeostasis in Epidermal Cells
The work is dedicated to the problem of the norm in the quantitative evaluation of metal content in the epidermal cells (hair) obtained by the method of spectrometry. Authors have analyzed the hair samples for Zn, Cu, an...
Induction of Antioxidant Capacity and Hydroxymethylfurfural Content Variations by Modifications of Cooked Fruit Processing.
Liège syrup is a Belgian traditional cooked fruit foodstuff, produced mainly from apples and pears. The process includes several hours of heating at high temperature during which complex chemical reactions occur, such as...