NEW CHITOSAN WOUND DRESSING – FIRST STEP - THE CYTOTOXICITY EVALUATION
Journal Title: Progress on Chemistry and Application of Chitin and its Derivatives - Year 2015, Vol 0, Issue
Abstract
The cytotoxicity of chitosan with polyvinox (PCH) and crosslinked chitosan (CH) was studied and analyzed. Cell viability was determined by thiazolyl blue formazan (MTT) assay and cell morphology observations were carried out during cell culturing and MTT tests. Crosslinked chitosan was used as a protective foil (scaffold) for skin wounds. Studies in vitro and the other obtained in this work results prove that the studied materials CH and PCH do not cause cytotoxic activity to Balb 3T3 mouse fibroblasts. CH and PCH are promising biomaterials with prospective application as wound healing dressings.
Authors and Affiliations
Ewa Karuga, Adam Zając, Zbigniew Rybak, Jerzy Hanuza
Keywords
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- EP ID EP73336
- DOI 10.15259/PCACD.20.09
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