New insights into the fecal microbiota of children living in a slum: association with small bowel bacterial overgrowth
Journal Title: Jornal de Pediatria - Year 2018, Vol 94, Issue 5
Abstract
The study by Mello et al. from the group of Dr. Mauro Batista de Morais provides additional information on the impact of living in a slum on small bowel bacterial overgrowth (SIBO), as well as some nutritional and anthropometric parameters, and adds new data on the fecal microbiota composition.1 Using real time-PCR technique, the authors compared the composition of the fecal microbiota of children with or without SIBO and presence of stunting and hemoglobin status and anemia. At total of 100 children, aged between 5 and 11 years, who lived in a slum in the outskirts of São Paulo, Brazil, were studied. SIBO was diagnosed by means of a hydrogen (H2) and methane (CH4) breath test (BT) following the ingestion of 10g lactulose. Results showed that 61% of the children studied had a BT compatible with SIBO and a lower mean height/age-score ([−0.48±0.90] vs. [−0.11±0.97]; p=0.027), as well as capillary hemoglobin ([12.61±1.03g/dL] vs. [13.44±1.19g/dL]; p<0.001). Children with SIBO presented a higher frequency of Salmonella spp. when compared to those without SIBO (37.7% vs. 10.3%; p=0.002). Higher counts of total Eubacteria (p=0.014) and Firmicutes (p=0.038) were observed in children without SIBO, while a higher count of Salmonella (p=0.002) was found in those with SIBO.
Authors and Affiliations
Carlos Lifschitz
Keywords
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- EP ID EP491085
- DOI 10.1016/j.jped.2017.12.002
- Views 43
- Downloads 0
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