New medicines and theirs adverse events in therapy of chronic HCV infection
Journal Title: Postępy Nauk Medycznych - Year 2010, Vol 23, Issue 10
Abstract
On beginning of years 90, recombined interferon use in therapy of patients with chronic HCV infection was effective at about 15%. Associating of this therapy from rybavirin, and then replacement recombined interferon by pegylated interferon improved antiviral of treatment effectiveness considerably.In this article were presented the researches on the efficiency and adverse effects of new interferons and nucleoside analogs in patients with HCV infection. In relation to the same group of the patients were discussed the latest results of the researches on the new antivirus preparations: inhibitors of protease or polymerase and cyclophilin inhibitors.Introduced investigations show, that multidirectional development of investigations over well-known and it will bring new antiviral medicines soon to best's tolerance of therapy, which will be she could be shorter guaranteing yet considerably higher antiviral effectiveness.
Authors and Affiliations
Tadeusz Łapiński, Robert Flisiak
Keywords
Related Articles
- EP ID EP53763
- DOI -
- Views 167
- Downloads 0
Factors contributing to the development of diseases of the oral mucosa and gums in children with type 1 diabetes
Introduction. Oral mucosal infections occur more often in patients with diabetes mellitus type 1 than in healthy population.Aim. The aim of the study was to analyze factors contributing to diseases of the oral mucosa and...
Przekazywanie sygnału TSH w komórkach tarczycy linii Nthy-ori 3-1
W poniższej pracy badano białka błonowe oraz wewnątrzkomórkowe szlaki sygnalizacyjne uruchamiane pod wpływem TSH w komórkach tarczycy linii Nthy-ori 3-1. Białka w solubilizowanych błonach komórkowych charakteryzowano met...
Signs and symptoms of dehydration in the elderly
Evaluation of the hydration status is probably the most difficult task in clinical examination.The clinical and objective determinations of hydration status frequently differ. Theintracellular water volume remains stable...
Bile duct injury complicating laparoscopic cholecystectomy: risk factors and prevention
Laparoscopic cholecystectomy is a most common performed operation in abdominal surgery. Steady progress in technical equipment used in this procedure not protects against the risk of bile duct injury yet. Problems concer...
Essential tremor in older people.
Essential tremor (ET) is a chronic neurological condition. Its prevalence substantially increases with age. Symptoms of ET become more severe in older patients and lead to marked disability. Clinical features of ET among...