News and comments: The 2018 Sjöberg Prize awarded for the unique treatment of acute promyelocytic leukemia
Journal Title: Traditional Medicine Research - Year 2018, Vol 3, Issue 2
Abstract
In February 2018, the Royal Swedish Academy of Sciences decided to award the 2018 Sj?berg Prize to Zhu Chen (Shanghai Jiao Tong University, China), Anne Dejean (Institute Pasteur, Paris, France), and Hugues de Thé (College de France, Paris, France) for their work on the clarification of molecular mechanisms and the development of a revolutionary treatment for acute promyelocytic leukemia (APL). Before the emergence of all-trans retinoic acid and arsenic trioxide, APL was thought to be one of the deadliest forms of cancer. Now, the five-year survival rate of this disease can reach more than 90% with the help of these two drugs. At the same time, these three scientists revealed the molecular mechanism underlying these drugs’ actions.
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