Next Step in Chronic Kidney Disease Therapy
Journal Title: Нирки - Year 2016, Vol 2, Issue 16
Abstract
Angiotensin-converting enzyme inhibitors/angiotensin receptor blockers are the basis of renoprotection therapy in chronic kidney disease. Parallel to decrease of glomerular filtration rate, there is an increase in the activity of the sympathetic nervous system, and the number of functioning nephrons reduces, which requires a change of treatment regimen. Reducing the risk of cardiovascular events on the background of increased hypertension probably dictates the need for a priority administration of sympatholytics, calcium channel blockers and angiotensin-converting enzyme inhibitors/angiotensin receptor blockers withdrawal. ARAMONEL formula: ARAMONEL — AR(B)A(CEI)MO(xonidine)NE(bivolol)L(ercandipine) is changed to MNELD — M(oxonidine)NE(bivolol)L(ercandipine)D(iuretic) that is used by us in recent years. Combined use of torsemide and xipamide is allowed. Angiotensin-converting enzyme inhibitors/angiotensin receptor blockers withdrawal requires evidence, which may be obtained in STOP-ACEi trial.
Authors and Affiliations
D. D. Ivanov
Keywords
Related Articles
- EP ID EP208349
- DOI -
- Views 71
- Downloads 0
Relevance of the modern renal biomarkers use for the screening of early development of preeclampsia
Pre-eclampsia is a unique multi-system disorder that occurs during the second half of pregnancy and is characterized by the arterial hypertension and proteinuria manifesting by heterogeneous disorders and adversely affec...
Hormone-dependent Nephrotic Syndrome, Relapsing Secondary to Allergy, in 9-year-old Child and its Treatment with Omalizumab
.
Male Infertility. Genetic Aspects
This review presents evidence of some genetic factors of male infertility and the methods that can be used for its diagnosis. Among the genetic factors there are being distinguished the genetic apparatus changes at the l...
Ciprofloxacin in Urinary Tract Infection Treatment
Urinary tract infections occupy a leading place among nephrological pathology and infectious diseases in general. The article deals with the aetiology and key stages of the pathogenesis of urinary system lesions. The mai...
Renal Morphological Changes in Experimental Systemic Vasculitis: Relation to Nephrotoxic Microelements
In the experiments on rats with a model of systemic vasculitis, it is shown that exogenous load on the body of nephrotoxic microelements, such as cadmium, lithium and molybdenum, affects the integral morphological indic...