Non-Specific Manifestations of Helminthiasis in Children
Journal Title: Здоров`я дитини - Year 2015, Vol 8, Issue 68
Abstract
The article deals with the non-specific manifestations of parasitic diseases. Clinical symptoms of these states are not only non-specific, but also have similarities with many different infectious and non-infectious diseases. This is the cause of incorrect diagnoses. In some cases, pathology simulate acute respiratory infections, bronchitis, urticaria, bronchial asthma and asthmatic bronchitis, eosinophilic pulmonary infiltrates, sometimes persistent blepharitis. In the clinical pattern of helminthiasis, vegetative and neurological symptoms often dominate that is due to pathogenetic features of helminthic intoxication. Furthermore, symptoms typical of acute leukemia, migratory eosinophilic pneumonia, abscesses, tumors of the soft tissues and bones may have parasitic origin. Various and non-specific manifestations of helminthiasis are crucial in laboratory diagnostics. One of the most popular drugs in the clinical practice of modern pediatrics among known broad-spectrum anthelmintics of benzimidazole group is albendazole (Vormil). Systemic action of Vormil is related to its active metabolite — albendazole sulfoxide, which is formed in the liver. The drug inhibits the polymerization of beta-globulin, resulting in violations in the formation of cytoplasmic microtubules of helminth cells, so this drug is active against different parasite species.
Authors and Affiliations
I. B. Yershova, H. O. Mochalova, I. A. Lokhmatova, M. H. Manashova, O. V. Petrenko
Colonic Motor Dysfunction in Children with Chronicle Constipation: Electrophysiological Aspects
Objective — to study соlonic electrical activity in children with chronic constipation. Patients and Methods. 63 children with chronic constipation (main group) and 30 apparently healthy children (control group) were obs...
The importance of correction of autonomic dysfunction in children with urinary disorders or How to improve the efficacy of neurogenic bladder therapy
The article presents a modern view on the problem of neurogenic bladder in children from the standpoint of awareness of the role of vegetative homeostasis. The importance of a differentiated approach to the correction of...
Genetic Polymorphism of Secretoglobin SCGB1A1 and Development of Lung Pathology in Children
The purpose of investigation — to study of A(38)G genetic polymorphism of the first exon of secretoglobin SCGB1A1 in Crimean children and to identify the possible correlation between the degree of polymorphism and develo...
Acute Streptococcal Tonsillopharyngitis in Children: Questions of Diagnosis and Therapy
The article presents the current views on approaches to diagnosis and rational therapy of acute tonsillopharyngitis in children.
Clinical and Immunological Features of Allergen-Specific Immunotherapy of Bronchial Asthma in Children
The article presents the results of a study on the clinical and immunological course of bronchial asthma depending on its phenotype and duration of specific immunotherapy. It is found that allergen-specific immunotherapy...