NON-ST-SEGMENT-ELEVATION ACUTE CORONARY SYNDROME: PREVENTION DRUG THERAPY
Journal Title: Българско списание за обществено здраве (Bulgarian Journal of Public Health) - Year 2018, Vol 0, Issue 1
Abstract
Nowadays, cardiovascular diseases (CVDs) that comprise a major portion of chronic non-communicable diseases are the leading cause of disease burdent and death in developed countries. The term acute coronary syndrome (ACS) covers any group of clinical symptoms consistent with acute myocardial ischemia. The classification of the ACS is based primarily on electrocardiogram (ECG) data. Depending on the ECG changes, the ACS is divided into patients with ST elevation (STE-ACS) versus patients with non-STelevation (NSTE-ACS). NSTE-ACS is increasingly the cause of hospitalization. There are conflicting views in the literature on the therapeutic strategies applied to different types of ACS. The strategies applied in the ACS need to take into account the patient‘s objective condition and accompanying illnesses to reduce shortand long-term mortality. Patients with NSTE-ACS are a non-homogeneous group against the risk of adverse cardiovascular events (MACE). The choice of a medical strategy for patients with NSTE-ACS is based on an individual case-by-case assessment. Cardioprotection is an integral part of the prevention of cardiovascular disease. The main purpose of prophylactic drug therapy in patients with cardiovascular diseases is to maximize the reduction of long-term risk for MACE and cerebrovascular disease; reducing recurrences and complications, requiring control of all identified risk factors. The purpose of this study is to review the literature on NSTE-ACS strategies in patients with a different risk profile and age; to determine which prophylactic drug therapy, tailored to the patient‘s objective condition and accompanying conditions, is assigned to patients with non-ST-elevation (NSTE-ACS) in order to prevent recurrences and complications.
Authors and Affiliations
Valentin Balabanski, Iliana Yaneva
Keywords
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