Norfloxacin Tinidazole induced Steven Johnsons Syndrome: A Case Report
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 11
Abstract
Introduction: Steven Johnsons Syndrome is a rare auto immune disorder which mainly includes skin and mucous membrane. It manifests as blisters on the skin, facial swelling and hyper pigmentation. Majority of the SJS cases are precipitated by drug therapy mainly by antibiotics. Case report: We report an unusual case of 45 year old Indian muslim female who received Nflox-TZ following which she had 4-5 episodes of diarrhoea and developed diffuse skin reaction which was diagnosed as SJS/TEN overlap. Past history revealed this as 3rd episode of skin reaction after the intake of same drug for the same indication. Conclusion: Our aim is to create an awareness through this report regarding the use of antibiotics injudiciously. Their benefit-risk profile needs careful evaluation as they can induce T cell-dependent reactions including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). Health care professionals must be careful before prescribing drugs that are known to have fatal reactions like SJS.
Authors and Affiliations
Anshu Kumar, Mrinal Kunj, U. S. P. Keshri, Vineet Kumar
Keywords
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