NOVEL COMPOUNDS WITH ANTIULCEROGENIC POTENTIALS UNVEILED IN PLANTAIN LEAVES ISOLATES (MUSA PARADISCIACA)
Journal Title: Journal of Drug Discovery and Therapeutics - Year 2017, Vol 5, Issue 2
Abstract
Ethanolic extract of plantain leaves was tested on forty eight ethanolic induced gastric ulcer rats for 28 days. The extract was found to posses potent antiulcerogenic effects. The isolates of such was analysed with Nuclear magnetic resonance (NMR) equipment and found to have antiulcerogenic compounds. The compounds have two carbon atoms without hydrogen bonding at 13C NMR with 29.430 PPM and at 62.097PPM of isolate A and B respectively. The isolates displayed same characteristics in hydrogen and carbon atoms indicating that they may be the same compound. This characterization has shown a structure of a compound that has not been characterized before and the new potent herbal drug for the treatment of gastric ulcer.
Authors and Affiliations
JIMMY| DEPARTMENT OF HUMAN PHYSIOLOGY, FACULTY OF BASIC MEDICAL SCIENCES, UNIVERSITY OF UYO, AKWA IBOM STATE, NIGERIA, E. O. | DEPARTMENT OF HUMAN PHYSIOLOGY, FACULTY OF BASIC MEDICAL SCIENCES, UNIVERSITY OF UYO, AKWA IBOM STATE, NIGERIA
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