Novel protocol for creation and study of abdominal aortic aneurysm with porcine pancreatic elastase infusion in rats
Journal Title: Αρχεία Ελληνικής Ιατρικής - Year 2015, Vol 32, Issue 6
Abstract
Abdominal aortic aneurysm (AAA) constitutes a serious threat for human life, especially the case where it is asymptomatic until rupture of the aneurysm, which is a common cause of death in subjects with AAA. There are no specific laboratory markers for distinguishing in a simple way between aneurysm bearers and the healthy population. Many biomarkers related to AAA outcome are not disease specific, due to their established correlation with atherosclerosis. Research is required to establish the underlying relations between these biomarkers and their role in AAA pathophysiology. With this experimental protocol, using the rabbit model, we aim to offer a conceptual description of potential biomarkers that will correlate with and predict the natural history of an AAA.
Authors and Affiliations
D. MORIS, C. BAKOYIANNIS, E. DOUSI, P. TSAKIROPOULOS, N. TSAKIROPOYLOS, S. GEORGOPOULOS
Keywords
Related Articles
- EP ID EP132883
- DOI -
- Views 55
- Downloads 0
Implementation of the objective structured clinical examination (OSCE) in the assessment of medical students <br /> <br />
The traditional evaluation of the clinical examination performed by medical students has some strengths but significant limitations, in terms of validity and reliability. The advent of the objective structured clinical e...
Needlestick injuries, compliance with universal precautions and clinical education of Greek<br /> medical students<br />
A questionnaire survey was undertaken of the 152 final-year students at the University of Ioannina Medical School. Its purpose was to establish the prevalence of needlestick injuries among the student population and to...
The translation-validation of the sense of coherence scale<br /> into Greek and its use in primary health care
OBJECTIVE Aaron Antonovsky’s Sense of Coherence (SOC) theory tries to explain why some people manage stress and stay well while others break down. According to Antonovsky, a strong SOC helps a person see the world as con...
Obsessive compulsive disorder: Neurobiological and neuropsychological substrate <br /> <br />
Obsessive-compulsive disorder (OCD) is a common and disabling psychiatric disorder. Significant progress has been made in the investigation of its neurobiological and neuropsychological substrate. From a neuroanatomical...
Superior vena cava syndrome and intracardiac thrombosis as early manifestations of Adamantiades-Behçet's disease
The case is presented of superior vena cava syndrome (SVCS) and intracardiac thrombosis as the initial manifestations of Adamantiades-Behçet's disease. A 32-year-old man was admitted to the department of internal medicin...