NT-ProBNP as a Diagnostic and Prognostic Marker in Case of NSTEMI Patients
Journal Title: Journal of Medical Science And clinical Research - Year 2014, Vol 2, Issue 8
Abstract
Background: Till date, myocardial infarction presents an alarming situation resulting in high morbidity and mortality. Non-ST elevation myocardial infarction (NSTEMI), becomes quite critical to diagnose from a specific biomarker. In this regard role of NT-proBNP as a prognostic marker in NSTEMI patients could be well considered. Aim: Objective of this study is to highlight diagnostic and prognostic value of NT-proBNP in treatment of NSTEMI patients. Methods: 60 NSTEMI patients from outpatient department at Institute of Post graduate Medical Education and Research, Kolkata for a period of six months starting from January 2014 to June 2014 along with 60 age matched controls were included in the study. Serum was collected by centrifugation of the samples at 1500g and stored at -80°C for further analysis. Within first 48 hrs of admission, a level of NT-proBNP was measured. Results were presented as mean ± SEM or number or percentages and further analysis was done by SPSS software. www.jmscr.igmpublication.org Impact Factor 3.79, ISSN(e)-2347-176x Arghyadip Sahoo et al JMSCR Volume 2 Issue 8 August 2014 Page 2107 JMSCR Volume||2||Issue||8||Page 2106-2113||August-2014 2014 Results: Among 60 NSTEMI patients, 7 patients expired. Rest 53 patients recovered after treatment and showed significant decline in the NT-proBNP level after treatment (3565 ± 4261 pg/ml vs pg/ml P<.0001). Conclusion: It can be aptly stated that for early diagnosis and further prognosis in NSTEMI patients, NTproBNP plays a crucial role.
Authors and Affiliations
Dr. Arghyadip Sahoo
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