Numerical evaluation of systematic errors of a non-invasive intracranial pressure measurement
Journal Title: Energetika - Year 2018, Vol 0, Issue 0
Abstract
Intracranial pressure (ICP) monitoring procedure can be applied to aid in secondary brain damage prevention. A high invasiveness of commonly used ICP measuring methods poses a risk of complications, and therefore new non-invasive methods are currently being developed. A promising non-invasive ICP measurement method is based on the existence of pressure balance state, which is driven by the unique morphological property of ophthalmic artery (OA). The value of ICP can be obtained by evaluating blood flow or artery characteristics in different OA segments, intracranial OA segment (IOA) and extracranial OA segment (EOA). In order to increase measurement accuracy, the systematic errors must be evaluated, which requires an implementation of a numerical model encompassing various physical phenomena. In this paper, a developed numerical model is presented, which was used to solve a transient fluid–structure interaction (FSI) problem of the pulsatile blood flow in a straight, physically meaningful anisotropic, hyperelastic OA, with ICP and external pressure (Pe) loads. It was found that the systematic error based on mean cross-sectional area difference between IOA and EOA segments was {–1.48, –1.37, –1.17} mmHg with ICP = {10, 20, 30} mmHg, respectively. The systematic error based on mean blood flow velocity difference between IOA and EOA segments was {–1.84, –1.76, –1.625} mmHg with ICP = {10, 20, 30} mmHg, respectively. The presented numerical model examined the worst-case scenario in terms of boundary conditions, which were immovable, while lengths of OA segments were physiologically relevant statistical means; however, the obtained systematic errors still met the clinical standards of ANSI/AAMI, where it is stated that the error should not exceed the ± 2 mmHg in the range of 0–20 mmHg of ICP. Boundary conditions and compliance affects the systematic error in both ways (reduce or increase it); this may explain the low systematic errors obtained in experimental studies by other authors.
Authors and Affiliations
Edgaras Misiulis, Gediminas Skarbalius, Algis Džiugys
Keywords
Related Articles
- EP ID EP435463
- DOI 10.6001/energetika.v64i3.3805
- Views 52
- Downloads 0
The use of mathematical models for the regulation of hydrogenerator voltage control
The problem of increasing the efficiency level of hydrogenerator voltage control with regard to its systemic role – the mobile power reserve of the energy system – is considered. An analysis of existing technical solutio...
International MITHYGENE-ETSON benchmark
Lithuanian Energy Institute scientists participated in the international MITHYGENE-ETSON benchmark and provided simulations of hydrogen combustion.In the case of a severe accident in a nuclear power plant,...
Comparative analysis of risks which are accompanied by the use of typical and boundary gases concentrations for the diagnostics of high voltage transformers
The aim of the scientific research provided in the article is to increase the operational reliability of high-voltage power transformers by reducing the possible risks when diagnosing high-voltage equipment based on the...
Efficient biomass value chains for heat production from energy crops in Ukraine
The purpose of the paper is to identify the most energy efficient value chains using solid biomass of specially grown energy crops and the most significant parameters affecting their energy efficiency and environmental s...
Numerical prediction of mechanical properties of zirconium alloy with hydrides using finite element method
During nuclear power plant (NPP) operation, degradation effects like ageing, corrosion, fatigue, and others may significantly impact component integrity. One of the degradation mechanisms is hydrogen absorption. High lev...