Obesity and Environmental Pollutants
Journal Title: Journal of Diabetes and Obesity - Year 2018, Vol 5, Issue 1
Abstract
Obesity is a global health problem in recent years Adipose tissue was known as a storage tissue increasing with rise of the body mass index the indicator of obesity The endocrine functions of adipose tissue might contribute to obesity diabetes mellitus cancer and infertility Many environmental chemicals affect actions of hormones so these chemicals have been defined as endocrine-disrupting chemicals EDCs or endocrine disruptors With the increase in production of EDCs in the world parallels the global obesity prevalence increases The reported rise in obesity of children under 2 years of age is also suggestive of alterations during development In early life EDCs exposure can influence epigenetic programming of obesity These pollutants can pass from mother to fetus via placenta and breast feeding Some obesogens are found in nature such as phytoestrogens and the others are mostly synthetic chemicals These chemicals commonly found in pesticides herbicides industrial and household products plastics detergents and personal care products These substances are defined persistant organic pollutant POPs and they accumulate in adipose tissue Common EDSs are Tributyltin TBT 4-Nonylphenol used in industry persistent organochlorines POPs used in agriculture industry diethylstilboestrol DES as a pharmaceutical bisphenol A BPA and phthalates used in plastics parabens as preservatives phytoestrogens in edible plants polybrominated diphenylethers PBDEs as flame retardants We searched current literature with the key words obesogens POPs endocrine disruptors in pubmed and filtered the results with articles in recent 5 years This mini reviewprovides current experience about association between obesity and endocrine disrupting chemicals
Authors and Affiliations
Binnur Okan Bakir
Keywords
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- EP ID EP418296
- DOI 10.15436/2376-0494.18.1693
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