Obesity, diabetes mellitus and oncopathology: epidemiological and pathogenetic aspects
Journal Title: Український терапевтичний журнал - Year 2018, Vol 0, Issue 3
Abstract
The review article is devoted to discussion of epidemiological and pathogenetic aspects of relationship between obesity, diabetes mellitus (DM) and oncopathology as well as to discussion of the data about the influence of therapeutical measures used in correction of obesity and DM on reduction of cancer risk. The data from epidemiological investigations studied a risk of oncomorbidity and mortality from oncologic causes among obese and diabetic persons are adduced. The important place is paid to discussion of association of oncorisk with metabolic disorders observed in obesity and type 2 DM as well as to mechanisms linked obesity, type 2 DM and oncopathology. The results from metaanalyses of investigations studied the influence of body weight loss on oncorisk and the data of experimental investigations studied the possibilities of antidiabetic therapy in the reduction of risk of development and progression of oncopathology are cited. The importance to reveal the main metabolic factors initiated and accelerated tumor growth aimed to their timely elimination is emphasized.
Authors and Affiliations
A. V. Chernyshov
Keywords
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- EP ID EP457593
- DOI 10.30978/UTJ2018-3-4-86
- Views 79
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