Obesity, inflammatory markers, total sialic acid, C - reactive protein (CRP).
Journal Title: INTERNATIONAL JOURNAL OF RECENT TRENDS IN SCIENCE AND TECHNOLOGY - Year 2017, Vol 22, Issue 1
Abstract
Problem Statement: Thyroid gland is one of the parts of our body which is constantly active metabolically and is one of the most responsive organs of the body. The thyroid gland turns out to be the endocrine organ in which the auto reactive processes have been known the longest. Anti thyroid antibodies are found in 3 – 8 % of individuals with no clinical evidence of Thyroid disease possibly signifying a subclinical focal thyroiditis. In the different thyroid disorders, the presence of anti-thyroid antibodies has been reported as 50 – 60%. Methods: 62 patients with different thyroid disorders (Colloid Nodular Goiter, inflammation and tumours) attending the various Medicine and surgical wards and the ENT dept. for their problems and who were subsequently sent to the pathology and biochemistry department of M.G.M. Medical College and L.S.K. Hospital, for investigations, were evaluated simultaneously for their autoimmune status and the morphological disease in the thyroid gland. Results: There are three primary antithyroid antibodies, the peroxidise antibodies (TPO), anti thyroglobulin antibodies (Tg) and anti (TSH) receptor antibody. While it was found to be 23% in the thyroid disorder group. Anti- TPO antibody alone was found to be positive in 5 patients(8.06%). Two of them had sub acute granulomatous thyroiditis. Conclusion: Strongly positive anti Tg and anti TPO antibody levels are diagnostic of Autoimmune thyroid disease. Retrospective review of all the antibody positive cases in other thyroid disease. All of the antibody positive cases need to be followed up. In the light of the clinical utility of the tests for anti thyroid antibodies in the diagnosis and prognosis of AITD.
Authors and Affiliations
Priakshi Baruah, Tarannum Sheereen, Aniruddha Mukherjee
Keywords
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