Obesity – the condition predisposing to vitamin D deficiency
Journal Title: Postępy Nauk Medycznych - Year 2012, Vol 25, Issue 3
Abstract
Obesity is nowaday well recognized as a global epidemic and is associated with various co-morbidities as cardiovascular diseases, diabetes, cancer (prostate, breast and colon cancer). Obese people are also predisposed to vitamin D deficiency. Vitamin D deficiency accelerates bone mass loss which decreases the mechanical resistance of bone tissue, but has also influence on other tissues and organs.<br>Vitamin D deficiency defined as serum 25-hydroxyvitamin D (calcifediol) concentration < 30 ng/ml has also been identified as a worldwide public health issue. It has been well observed that obese individuals frequently have low circulating calcifediol concentration. The possible cause of vitamin D deficiency is avoiding the solar radiation (which comprises the UVB fraction responsible for the synthesis of the vitamin D in the skin), impaired vitamin D skin synthesis or sequestration of the vitamin D in the fatty tissue.<br>In this review we would like to present what is the relationship between low circulating 25-hydroxyvitamin D concentration and obesity and what is the possible role of adipose tissue as an endocrine system in vitamin D metabolism.
Authors and Affiliations
Michał Wąsowski, Ewa Czerwińska
Keywords
Related Articles
- EP ID EP54416
- DOI -
- Views 131
- Downloads 0
Diagnosis of mushroom poisoning in emergency department
Mushroom poisoning causing phalloides syndrome is a health hazard. Mortality in these poisonings is 10-60%. Fast implementation of specific treatment is indeed one factor influencing the prognosis. Hence, the proper diag...
Adiponectin, Leptin and Resistin in women with policystic ovary syndrome
Background: Polycystic ovary syndrome (PCOS) belongs to the most frequent endocrine disorders found in women of reproductive age. It is characterized by several abnormalities in different grade of frequency and intensity...
Can we diagnose ankylosing spondylitis earlier?
Ankylosing spondylitis is the most common disease belonging to so called axial spondyloarthritis. The disease is characterised by inflammatory back pain, sacroilitis detected radiologically and impaired spinal mobility....
Postępy w rozpoznawaniu szpiczaka plazmocytowego oraz rekomendacje dotyczące leczenia
Szpiczak plazmocytowy jest wieloetapowo przebiegającą chorobą charakteryzującą się rozrostem i akumulacją monoklonalnych plazmocytów. Etiologia choroby jest nieznana. Translokacje w obrębie genów łańcucha ciężkiego immun...
Terson’s syndrome – case presentation and therapeutic management
Terson’s syndrome initially was defined as intravitreal haemorrhage in combination with subarachnoideal bleeding.Presently the name of this syndrome comprises all cases of intraocular haemorrhages in the course of intrac...