Observation on the effect of modified buffy coat centrifugal canning method on improving the quality of platelet concentrates
Journal Title: Chinese Journal of Blood Transfusion - Year 2023, Vol 36, Issue 2
Abstract
Objective To evaluate the quality of platelet concentrates (PCs) prepared by traditional and modified buffy coat centrifugal canning methods, and to explore the effect of modified buffy coat centrifugal canning method on improving the quality of PCs. Methods The buffy coat centrifugal canning methods was divided into traditional group and modified group. In the traditional group, the buffy coat component bag and empty bag were directly combined layer by layer and vertically canned for light centrifugation. In the modified group, a foam spacer was added between the buffy coat component bag and the empty bag for light centrifugation layer by layer. The effects of the two groups of centrifugal canning methods on the preparation quality of PCs were observed. Results The platelet content in PCs prepared by the modified buffy coat centrifugal canning method was significantly higher than that in the traditional group, and the mixed amount of red blood cells was lower than that in the traditional group (P<0.05). Although there was no statistically significant difference in the qualified rate of platelet content between the two groups (P>0.05), the qualified rates of platelet content and mixed red blood cell in the modified group were higher than those in the traditional group (P<0.05). Conclusion The modified centrifugal canning method with buffy coat can improve the quality of PCs, which is convenient and cheap, and is worth popularizing.
Authors and Affiliations
Manhua LUO, Meiyan KANG, Jin LI, Xianbin WU
Keywords
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- EP ID EP738499
- DOI 10.13303/j.cjbt.issn.1004-549x.2023.02.025
- Views 34
- Downloads 0
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