OCHRONOSIS- A CASE REPORT
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 22
Abstract
PRESENTATION OF CASE Connective tissue is generally affected in ochronosis. Recognition of changes secondary to the deposition of ochronotic pigments has increased with advances in diagnostic technology, allowing both improved imaging and early biochemical and genetics-based diagnosis of alkaptonuria, the cause of ochronosis. Successful symptomatic treatment of ochronotic arthropathy with joint replacement has been documented and a new pharmacotherapeutic agent, Nitisinone is currently used for both prevention and treatment of ochronosis. A 53 years old male came with the complaints of pain and stiffness in both knee joint and lower back pain for the past 3 years. He was intermittently treated with analgesics without total relief. There was gradual deterioration of the symptoms in the knee joint with restricted movements, which forced him to report to an orthopaedic surgeon. Later on, was taken for bilateral meniscectomy. After surgery, was put on palliative treatment and drug Nitisinone was advised.
Authors and Affiliations
Kanika Bansal, Rakesh Kakkar
Keywords
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- EP ID EP433357
- DOI 10.14260/jemds/2018/614
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