One of Curious Congenital Midline Abdominal Defects in Newborn: A Giant Omphalozele in a 3 Years-Old Boy
Journal Title: Journal of Regenerative Biology and Medicine - Year 2021, Vol 3, Issue 4
Abstract
Omphalocele is one of the congenital abdominal wall defects and specifically refers to an umbilical ring defect in which the abdominal organs protrude in front of the abdominal wall in a thin sac or membrane. Such an abdominal wall defect develops around the third week of pregnancy due to the failure of adhesion between the embryonic lateral abdominal wall components. The condition occurs in 1 in 5,000 children, with boys more commonly affected than girls [1,2,3,9]. Overall, it is a rare disease whose therapy requires the experience of proven specialists [1-9,13-17]. For this purpose, pediatric surgeons are available to assist children and their parents from the time of diagnosis in the womb through direct care in the delivery room and, if necessary, further surgery to follow-up treatment. Through close and direct contact with the individual physicians, one can achieve an optimal and most comfortable care situation for the child. During embryonic development, part of the intestine emerges from the abdominal cavity of the embryo into the amniotic cavity to turn around. As the pregnancy progresses, the intestine return to the abdomen of the child, and the abdominal wall closes. If the abdominal wall does not close or closes incompletely, an abdominal wall defect results, and parts of the abdominal organs (mostly the intestine) are located further outside the abdominal cavity. In some cases, the intestine is covered by a membrane of the umbilicus.
Authors and Affiliations
Stefan Bittmann, Gloria Villalon, Elena Moschüring-Alieva, Elisabeth Luchter
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