One Week Post Natal Changes in Neonatal Lipid Profile Values and Its Association with Gestational Age: A Prospective Study in North India
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2014, Vol 2, Issue 2
Abstract
Adult serum lipid disorders have their root in childhood. Most of the past studies have measured lipid profiles at birth and the next measure earliest at 6 months after birth. The aim of this study was to estimate the neonatal lipid profile values at birth and 1 week of age & look for association of these values with birth weight and gestational age. 504 singleton live-borns from a tertiary care centre were studied. Lipid profiling was done using standard procedures. Data was compiled and analyzed using SPSS-15 for significance of difference in means by unpaired t-test. There was no significant difference in mean lipid values based on birth weight. The preterms had an unhealthier lipid profile. The overall change in mean lipid values over one week was highly significant. The increase in values for pre-terms was more sluggish. In conclusion, there is a rapid change in lipid profile post birth even as early as one week. Pre-terms are at greater atherosclerotic risk due to unhealthier lipid profile.
Authors and Affiliations
Pushpendra Magon, R. S Bharatwaj
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