Original Research article: A Study of Lipoprotein (a) and other risk factors in middle aged coronary heart disease subjects
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2015, Vol 3, Issue 6
Abstract
Ischemic heart disease (IHD) is one of the most important causes of morbidity and mortality. Lipoprotein ‘a’ modulates the risk of IHD in patients with hypercholesterolemia and lipoprotein excess is commonly detected in man and women with premature IHD. The main aim is To measure and Compare the level of Lipoprotein ‘a’ and lipid profile between young patients of acute myocardial infarction (MI) and in healthy normal controls. The method was in these study 250 patients of acute MI below 40 year age group along with age and sex matched 45 healthy controls are selected. Fasting Blood samples were collected from all participants for estimation of serum lipid profile and Lipoprotein ‘a’. The results were the mean concentration of serum cholesterol(mg/dl), Serum TG(mg/dl), Serum HDL(mg/dl), Serum VLDL(mg/dl), serum LDL(mg/dl)and Lipoprotein ‘a’(mg/dl) in Acute MI patients is 198.52± 27.94, 187.28 ± 49.25, 38.52 ± 4.82, 37.45 ± 9.85, 122.64± 30.04, 28.44 ± 5.06 as compared to 177.23 ± 28.69, 146 ±32.5, 45.80 ± 4.69, 29.20 ± 6.5, 102.73 ± 28.43, 16.43 ± 4.02 in control group. The conclusion In this present study serum cholesterol, Serum TG, Serum LDL, Serum VLDL level were found to be raised along with low level of serum HDL and elevated level of serum Lipoprotein ‘a’ in patients of acute MI as compared to controls. Keywords: Lipoprotein ‘a’, young age group, IHD
Authors and Affiliations
Dr. R J Chhabra, Dr. Shweta Singh, Dr. Neeta Kapai, Dr. Ketan Mangukiya
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