Role of Nebulised Lignocaine With Midazolam In Flexible Bronchoscopy in Reducing Patient Cough , Discomfort & Study the Side Effects of Nebulised Lignocaine in Patients Undergoing Fibro Optic Bronchoscopy Scope
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 5
Abstract
Abstract: Topical anesthesia for flexible bronchoscopy can be achieved in several ways like administration of an anesthetic agents by injecting through cricothyroidmembrane,by giving drug lignocaine through Nebulization, 3}administering the drug through oral spray. Nebulization of lidocaine can achieve very satisfying anesthesia comparable to oral spraying with significant low plasma levels of the drug. Nebulization of lidocaine with midazolam gives good results than using only lidocaine without sedation. Nebulization of lidocaine gives effective analgesia & the dose of conscious sedation is significantly reduced. So we studied the effect of nebulized lignocaine with midazolam as sedation in 60 patients needing bronchoscopy and compared them to 50 patients who underwent fibrooptic bronchoscopy with oral spray of lignocaine and midazolam as sedation.This is a study of 110 patients undergoing bronchoscopy were subjected to conscious sedation& local anaesthesia in Govt general hospital Osmania medical college for a period of two years.Patients were in the age group of 25 to 75 years. After obtaining consent, 60study cases were given nebulization. With lidocaine& sedation with midazolam. Control group had bronchoscopy with oral spray of drug lignocaine and midazolam given for sedation .All patients had Intravenous lines, pulse oximetry monitoring of saturations, serial recordings of their blood pressure, pulse, respiratory rate were noted. All patients received supplemental oxygen through oral mask at the rate of 1-2 liters per minute. In study group, patients had 4 ml of lidocaine diluted in 4 ml of normal saline by nebulization for 15 minutes, beforebronchoscopy,control patients had lidocaineoral spraying before bronchoscopy. After the procedure patients perception of discomfort ,their severity of cough ,were analyzed ,discomfort status was perceived by administration of visual analog scale, heart rate, breathing patterns, blood pressure and continuous pulse oximetry readings in both groups are compared. Patients undergoing bronchoscopy after nebulization with lignocaine have less intensity of cough,they tolerate the procedure better than placebo group, experience less discomfort during bronchoscopy. Oxygen saturation is well maintained in studygroup. These patients needed less dose of midazolam for conscious sedation. Statistical analysis was performed by calculating mean, P Value. Standard Deviation , Anova For Cough Score By Patients & Physicians, Anova For Discomfort Score ,Anova For Total Lignocaine Dose in both groups. Nebulised lignocaine with midazolam sedation before bronchoscopy is safe .These patients undergo bronchoscopy procedure better than control group. They have less cough .stable vital parameters, less discomfort during and after procedure. Keywords:bronchoscopy, nebulization, sedation
Authors and Affiliations
K Ramesh Kumar, K. Subhakar, M. Madhusudan Reddy
Keywords
Related Articles
- EP ID EP372294
- DOI -
- Views 60
- Downloads 0
Correlation between Advanced Oxidation Protein Products (AOPP) and Antioxidant status in Type 2 diabetics in Southern Asian Region
Incidence & prevalence of type 2 DM is increasing in worldwide but greatest prevalence in Asian population as also its chronic complications. Oxidative stress is believed to be a common pathogenic factor for these grave...
Some Platelet parameters in patients with HCV-Associated Chronic Liver Diseases
Egypt has the highest hepatitis C virus (HCV) prevalence all over the world. Thrombocytopenia is a common finding in subjects with chronic hepatitis C. The aim of the study was to measure different platelet parameters in...
Study of Etiological Profile of Neonatal Sepsis in a Tertiary Care Hospital: SMS Medical College, Jaipur
Abstract: This study was conducted to know the prevalence and bacteriological profile of neonates admitted for suspected sepsis in a tertiary care hospital of Rajasthan. In the present study, 1054 neonates with signs and...
Impact evaluation: A Community-based cross sectional study to know the awareness and practice of Janani Suraksha Yojana (JSY) among the beneficiary in Sanathal PHC, Ahmedabad, Gujarat
Abstract: In 2005, with the goal of reducing the numbers of maternal and neonatal deaths, the government of India launched Janani Suraksha Yojana (JSY) , a conditional cash transfer scheme, to incentivize women to give...
Cholelithiasis and Nephrolithiasis in Two Infants with Down’s Syndrome: A Case Report
Cholelithiasis in infants and children is rare. There are very few reports of cholelithiasis in infants with Down’s syndrome. Here we are reporting two cases of Down’s syndrome aged 3 months and 6 months respectively in...