Optical coherence tomography in diagnosis of early primary open angle glaucoma
Journal Title: Guoji Yanke Zazhi - Year 2018, Vol 18, Issue 5
Abstract
AIM: To evaluate the clinical value of retinal nerve fiber layer(RNFL)thickness, optic disc parameters and macular thickness by optical coherence tomography(OCT)in early diagnosis of primary open angle glaucoma(POAG). <p>METHODS: Sixty-five patients(eighty-five eyes)were selected as a study group and fifty-two normal people(seventy-eight eyes)were selected as a control group. The retinal nerve fiber layer thickness, optic disc parameters, including cup/disc(C/D)rate, cup area(CA), cup volume(CV), disc area(DA), rim area(RA)and rim volume(RV), and macular thickness were detected by Cirrus HD-OCT. The data were compared and analyzed. <p>RESULTS: The retinal nerve fiber layer thickness of superior, inferior, temple, nasal and average in the study group were all significantly thinner than those of the control group(<i>P</i><0.001). The cup area, cup volume and cup/disc ratio in the study group were significantly higher than those of the control group(<i>P</i><0.001); while the rim area and rim volume in the study group were significantly lower than those of the control group(<i>P</i><0.001). But the disc area was not significantly different between two groups(<i>P</i>>0.05). The macular thickness of superior, inferior, temple and nasal in the study group were all significantly thinner than those of the control group(<i>P</i><0.001). <p>CONCLUSION: OCT can detect the change of retinal nerve fiber layer thickness, optic disc parameters and macular thickness, it is helpful for early diagnosis of POAG.
Authors and Affiliations
Zhi-Li Cui
Keywords
Related Articles
- EP ID EP656688
- DOI 10.3980/j.issn.1672-5123.2018.5.35
- Views 115
- Downloads 0
Consecutive exotropia: risk factors and treatment progress
Consecutive exotropia is not uncommon in clinical practice, but the domestic researches on the disease and its risk factors are rare. This article aims to summarize the risk factors of consecutive exotropia after surgery...
Observation of transscleral cyclophotocoagulation for glaucoma secondary to vitrectomy
AIM: To evaluate the clinical efficacy and safety of transscleral cyclophotocoagulation(TSCP)for glaucoma secondary to vitrectomy. <p>METHODS: A retrospective review was performed within 20 patients(20 eyes)with glaucoma...
Correlation of serum miR-146a with nuclear factor -κB and vascular endothelial growth factor in diabetic retinopathy patients
AIM:To investigate the correlation of serum miR-146a with nuclear factor-κB(NF-κB)and vascular endothelial growth factor(VEGF)in diabetic retinopathy patients. <p>METHODS: A total of 100 patients with T2DM treated in our...
Comparison between time-domain and spectral-domain OCT in the detection of retinal nerve fiber layer defects in glaucoma patients
AIM: To compare the use of the instruments' built-in normative databases, the sensitivities of time-domain optical coherence tomography(Stratus OCT)and spectral-domain OCT(Spectralis OCT)in the detection of retinal nerve...
Treatment of diabetic retinopathy macular edema by combination of Qi Ming Granule and macular grid laser photocoagulation
AIM: To investigate the clinical efficacy of Qi Ming granule combined with macular grid laser photocoagulation in the treatment of diabetic retinopathy(DR)with diabetic macular edema(DME). <p>METHODS: The clinical data o...