Optical coherence tomography in diagnosis of early primary open angle glaucoma
Journal Title: Guoji Yanke Zazhi - Year 2018, Vol 18, Issue 5
Abstract
AIM: To evaluate the clinical value of retinal nerve fiber layer(RNFL)thickness, optic disc parameters and macular thickness by optical coherence tomography(OCT)in early diagnosis of primary open angle glaucoma(POAG). <p>METHODS: Sixty-five patients(eighty-five eyes)were selected as a study group and fifty-two normal people(seventy-eight eyes)were selected as a control group. The retinal nerve fiber layer thickness, optic disc parameters, including cup/disc(C/D)rate, cup area(CA), cup volume(CV), disc area(DA), rim area(RA)and rim volume(RV), and macular thickness were detected by Cirrus HD-OCT. The data were compared and analyzed. <p>RESULTS: The retinal nerve fiber layer thickness of superior, inferior, temple, nasal and average in the study group were all significantly thinner than those of the control group(<i>P</i><0.001). The cup area, cup volume and cup/disc ratio in the study group were significantly higher than those of the control group(<i>P</i><0.001); while the rim area and rim volume in the study group were significantly lower than those of the control group(<i>P</i><0.001). But the disc area was not significantly different between two groups(<i>P</i>>0.05). The macular thickness of superior, inferior, temple and nasal in the study group were all significantly thinner than those of the control group(<i>P</i><0.001). <p>CONCLUSION: OCT can detect the change of retinal nerve fiber layer thickness, optic disc parameters and macular thickness, it is helpful for early diagnosis of POAG.
Authors and Affiliations
Zhi-Li Cui
Keywords
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- EP ID EP656688
- DOI 10.3980/j.issn.1672-5123.2018.5.35
- Views 101
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