Oral Anticoagulants for Prophylaxis of Deep Vein Thrombosis in Lower Limb Surgeries: The Indian Perspective
Journal Title: Journal of Bone and Joint Diseases - Year 2017, Vol 0, Issue 0
Abstract
Background: DVT is a fatal complication in patients undergoing lower limb surgeries. Not much evidence is provided in Indian literature regarding the incidence of DVT and ideal prophylaxis for the same. Oral Anticoagulants are now commonly used for chemoprophylaxis against DVT. Our study is to identify the role of Oral Anticoagulants for prophylaxis against DVT in lower limb orthopaedics surgeries. Material and method: The present study is a prospective study for the role of oral anticoagulants in prophylaxis against DVT in patients with lower limb surgeries carried out over a period of two years. Total of 110 patients were selected based on inclusion and exclusion criteria. Randomization was done by simple randomization technique and patients were divided into two groups of 55 patients each. Group 1 (case) received Dabigatran Etexilate(150mg) (oral anticoagulant) whereas group 2 (control) didn’t receive any prophylaxis following which Color Doppler was performed on all patients. Result: Overall incidence of Deep Vein Thrombosis in our study group was found to be 23.6%, of which incidence of DVT in case group was 16.36% compared to control group in which incidence of DVT was found to be 30.9%, hence statistical significant difference (p value<0.05) of incidence was found in both groups. Duration of surgery and patient’s age were two most significant risk factors associated with the occurrence of DVT. Conclusion: Deep Vein Thrombosis is relatively less common in Indian patients compared to the western population but recent data shows that there is need of use anticoagulants in Indian population due to increasing life expectancy and sedentary lifestyles and Oral Anticoagulants are now a safe and effective method for prophylaxis against DVT.
Authors and Affiliations
Chandra Prakash Pal, Vivek Mittal, Vipul Agarwal, Shamrendra Narayan, Ashwani Singh, Lokesh Kumar Singh
Keywords
Related Articles
- EP ID EP508967
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