Oral immunization of dogs against rabies
Journal Title: Бюлетень "Ветеринарна біотехнологія" - Year 2017, Vol 31, Issue
Abstract
ntroduction. Although the main source of rabies in Ukraine is red fox, however, epizooty of the rabies is characterized by "natural" and "urban" manifestation with a significant number of cases in cats (24.5%) and dogs (18.5%). Taking into account the certain imperfection of the parenteral route of introducing vaccines, there is a need for studies on oral vaccination of dogs.The goal of the work. Carry out a study on the effectiveness of the “Brovarabis V-RG” vaccine for stray dogs in the field.Materials and methods. To evaluate the number of stray dogs we used a methodology developed by the World Society for the Protection of Animals (WSPA). 100 (twice 50) doses of the vaccine “Brovarabis V-RG” (series 030516) were used for oral vaccination, which were distributed twice by 5 doses with 7 days interval in 10 different places of three different sectors of Urban-type settlement Ripky in Chernihiv oblast in the areas, where stray dogs was detected. Anti-rabies immunity was evaluated in caught dogs in 30 days.Results of research and discussion. After town investigation, we detected 62 stray dogs. The majority of the animals was concentrated in the central part of the town not far from the waste disposal sites, near the park and market.After assessing of the stray dogs population, 50 doses of the vaccine were distributed. After 7 days, 50 vaccine baits where distributed in the same places. In total, 42 of 100 vaccine baits that were distributed twice confirmed to be “lost”, which means that consumption rate was 42%. 12 dogs were caught to assess anti-rabies immunity. The research revealed titers of anti-rabies antibodies in the range of 1.37-3.37 IU/cm3 in three blood serum samples of stray dogs, meaning the level of seroconversion to the rabies virus was 25.0%.Conclusions and prospects for further research. The conducted researches demonstrated the principle possibility of using the method of oral vaccination against rabies of stray dogs in the territory of cities.
Authors and Affiliations
Nikolai Golik, Ivan Polupan, Serghiy Nychyk, J. Sharai, Vitalii Nedosekov
Keywords
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- EP ID EP266016
- DOI 10.31073/vet_biotech31-05
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