Oral premedication in children: Comparison of combination of midazolam-ketamine and oral midazolam- A Randomised trial
Journal Title: Indian Journal of Clinical Anaesthesia - Year 2018, Vol 5, Issue 2
Abstract
Introduction Premedication with sedative drugs is often used in paediatric practice as one of the modalities to reduce preoperative anxiety in children undergoing surgery It reduces both patient and parental anxiety and improves overall satisfaction Also provides anterograde amnesia and reduces postoperative behavioral changes and adverse outcomes in children The ideal premedication in children should be readily acceptable and should have speedy and reliable onset with negligible side effectsMaterials and Methods After obtaining institutional medical ethics committee approval sixty ASA physical status I or II children aged 18 years scheduled for elective surgery were randomly allocated into one of the two groups Group M n30 received preservative free oral midazolam 05mgkg 1ml5mg acetaminophen based syrup 5ml120mg upto maximum value of 04mlkg Group MK n30 received preservative free oral midazolam 025 mgkg 1ml5mgwith 3mgkg oral ketamine1ml50mg acetaminophen based syrup 5ml120mg upto maximum value of 04mlkgResults Combination of midazolam025mgkg and ketamine3mgkg provided faster onset and higher degree of sedation comparable incidence of satisfactory parental separation and mask acceptance without any added side effects in comparison to midazolam 05mgkgConclusion Addition of low dose ketamine to midazolam as a premedication provides adequate sedationKeywords Premedication Midazolam Ketamine Pediatric patients Sedation
Authors and Affiliations
Chiteshwar Walia, Pankaj, Manjunath Prabhu, Daniel Thomas
Keywords
Related Articles
- EP ID EP476464
- DOI 10.18231/2394-4994.2018.0046
- Views 84
- Downloads 0
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