ORAL SUSTAINED RELEASE DRUG DELIVERY SYSTEM: AN OVERVIEW
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 5
Abstract
In the recent years, focus on the development of oral controlled release drug delivery systems has increased. Oral ingestion has been the most convenient and commonly employed route of drug delivery. Indeed, for sustained-release systems, the oral route of administration has by far received the most attention with respect to research on physiological and drug constraints. Sustained release dosage forms are designed to release a drug at a predetermined rate by maintaining a constant drug level for a specific period of time with minimum side effects. Sustained release of drugs in gastrointestinal tract following oral administration is not affected by the absorption process. Here this article concentrates on preparations, factors influencing, design, formulation, and the evaluation of oral sustained release preparations. The principal goal of sustained release dosage forms is the improvement of drug therapy assessed by the relationship between advantages and disadvantages of the use of sustained release systems.
Authors and Affiliations
Isha Chugh , Nimrata Seth , A. C. Rana , Surbhi Gupta
Keywords
Related Articles
- EP ID EP124943
- DOI -
- Views 120
- Downloads 0
A COMPREHENSIVE REVIEW ON ANTIMICROBIAL ACTIVITY OF 1,3,4-OXADIAZOLE DERIVATIVES
Heterocyclic compounds possess diverse biological properties that has lead to intense study and research of these compounds. One of these compounds is oxadiazole which has been found to exhibit various pharmacological a...
METHODS OF SIZE REDUCTION AND FACTORS AFFECTING SIZE REDUCTION IN PHARMACEUTICS
Within pharmaceutical manufacturing, size reduction is one of the most extensively used and vital unit operations. Size reduction is a process of reducing large solid unit masses into small unit masses, coarse part...
DRUGS CAUSING OROFACIAL PIGMENTATION: AN OVERVIEW OF LITERATURE
The term “Oro-facial pigmentation” refers to a wide range of lesions or conditions featuring a change of color of Oro-facial tissues. Pigmentation of the Oro-facial tissues is seen in certain races or ethnic groups such...
PULSATILE DRUG DELIVERY SYSTEMS USING NATURAL POLYMERS AS RELEASE MODIFIERS
Sustained and controlled drug delivery system release the drug at a substantially steady rate of release per unit of time. However, there are instances where maintaining a constant blood level of a drug is not desirable....
ACETONE EXTRACT OF CRINUM JAGUS BULBS (LILLIACEAE): AN ACUTE AND SUB CHRONIC TOXICOLOGICAL EVALUATION IN ALBINO RATS
The bulbs of Crinum jagus bulbs are used in the treatment of various ailments in traditional medicine. This study was aimed at evaluating the toxicity of acetone extracts of Crinum jagus bulbs on albino rats following ac...