ORALLY DISINTEGRATING TABLETS: A REVIEW
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 4
Abstract
Orally disintegrating tablets (ODTs) are gaining prominence as new drug delivery systems and emerged as one of the popular and widely accepted dosage forms, especially for the pediatric and geriatric patients. To obviate the problem of dysphagia and to improve patient compliance, ODTs have gained considerable attention as preferred alternatives to conventional tablet and capsule formulations. Various scientific techniques including freeze drying, moulding, spray drying, sublimation, direct compression, cotton candy process, mass extrusion, melt granulation etc. have been employed for the development of ODTs. These techniques render the disintegration of tablet rapidly and dissolve in mouth without chewing or additional water intake. The current article is focused on ideal characteristics, significant features, patented technologies, formulation aspects including the use of superdisintegrants. Various marketed preparations along with numerous scientific advancements made so far in this avenue have also been discussed.
Authors and Affiliations
Vinod Mudgal , Pooja Sethi , Rajat Kheri , G. K. Saraogi , A. K Singhai
Keywords
Related Articles
- EP ID EP155825
- DOI -
- Views 90
- Downloads 0
FLUORIDE TOXICITY – A HARSH REALITY
There are many incidents of fluoride toxicity whether it is acute or chronic. Fluoride toxicity is an environmental hazard which arises from the upper layers of geological crust and is dissolved in water. Prolonged drink...
SYNTHESIS AND CHARACTERIZATION OF 5-SUBSTITUTED SERIES OF 3-(4-CHLOROPHENYL)-2,4-DITHIO-1,3,5-TRIAZINES CONTAINING CHALCONE MOITIES
Present research comprises, isomerisation of series of (2E)-1-{4-[2-(4-chlorophenyl)imino-4-substitutedimino)amino-1,3,5-dithiazino-6-yl]aminophenyl}-3-(3,4-dimethoxyphenyl) prop-2-en-1-one (Ia-e) were successfully carri...
ANTICONVULSANT ACTIVITY OF WHOLE PLANT OF SOLANUM SURATTENSE BURM AGAINST MES AND PTZ INDUCED SEIZURES IN RATS
The anticonvulsant activity of whole plant of Solanum surattense was assessed by successive hot soxhlet extraction using Petroleum-ether (40-600C), Chloroform, and Methanol respectively and finally with Water maceration...
ORAL MULTIPARTICULATE PULSATILE DRUG DELIVERY SYSTEMS: A REVIEW
Pulsatile drug delivery aims to release drugs in a planned pattern i.e. at appropriate time and/or at a suitable site of action. Pharmaceutical invention and research are increasingly focusing on delivery systems which e...
PHYTO CHEMICAL SCREENING AND ANTI- OXIDANT ACTIVITY OF ETHANOLIC EXTRACT OF HELIOTROPIUM INDICUM
The aim of the present study was to investigate phyto chemical screening and anti-oxidant activity of the ethanol extract of the whole plant of Heliotropium indicum. The ethanolic extract of the whole plant of Heliotropi...