Oscillations in Biological Systems: Psychopathological Associations
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2019, Vol 16, Issue 4
Abstract
The sum of unconnected causes tends toward a gaussian distribution as a limit and that the sum of random causes is manifested as cyclical series. In contrast to the classical thermodynamic systems in which stability is maintained through energy conservation, and energy loss leads to instability and disorganization, biological systems are dissipative nonlinear, far-from-equilibrium structures in which stability is the result of energy dissipation. The fundamental source of energy in living systems is ATP which, in one of its major modes, is generated by glucose glycolysis through the biochemical oscillations of phosphofructokinase according to the nonlinear kinetics of nonequilibrium thermodynamic systems. At the molecular level this energy is transmitted by the vibrational deformation of antisymmetric solitons. Given that living systems are inserted in a geophysical state determined by the parameters of the rotation of the earth and the consequent alternation of light and dark occurring in different cycles through yearly seasonal variations, the critical importance of circadian oscillations, the key role played by the light-dependent enzyme N-acetyltransferase in controlling circadian cycles through serotonin-melatonin transformations, and the importance of maintaining a complex pattern of reciprocal balances between the multiplicity of interlocking circadian, ultradian, and circannual oscillations immediately follows [11-20]. At all levels of biological organization, stability as a result of reciprocal oscillations of key components is apparent; in hormonal systems such as LHRH-LH-testosterone where the oscillatory solution corresponds to stability or in the pituitary thyrotropin-thyroxin-intermediary enzyme interaction in which stability hinges on the steady-state solution.
Authors and Affiliations
Pierre Flor Henry
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