Oscillations in Biological Systems: Psychopathological Associations
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2019, Vol 16, Issue 4
Abstract
The sum of unconnected causes tends toward a gaussian distribution as a limit and that the sum of random causes is manifested as cyclical series. In contrast to the classical thermodynamic systems in which stability is maintained through energy conservation, and energy loss leads to instability and disorganization, biological systems are dissipative nonlinear, far-from-equilibrium structures in which stability is the result of energy dissipation. The fundamental source of energy in living systems is ATP which, in one of its major modes, is generated by glucose glycolysis through the biochemical oscillations of phosphofructokinase according to the nonlinear kinetics of nonequilibrium thermodynamic systems. At the molecular level this energy is transmitted by the vibrational deformation of antisymmetric solitons. Given that living systems are inserted in a geophysical state determined by the parameters of the rotation of the earth and the consequent alternation of light and dark occurring in different cycles through yearly seasonal variations, the critical importance of circadian oscillations, the key role played by the light-dependent enzyme N-acetyltransferase in controlling circadian cycles through serotonin-melatonin transformations, and the importance of maintaining a complex pattern of reciprocal balances between the multiplicity of interlocking circadian, ultradian, and circannual oscillations immediately follows [11-20]. At all levels of biological organization, stability as a result of reciprocal oscillations of key components is apparent; in hormonal systems such as LHRH-LH-testosterone where the oscillatory solution corresponds to stability or in the pituitary thyrotropin-thyroxin-intermediary enzyme interaction in which stability hinges on the steady-state solution.
Authors and Affiliations
Pierre Flor Henry
Keywords
Related Articles
- EP ID EP590758
- DOI 10.26717/BJSTR.2019.16.002891
- Views 168
- Downloads 0
Aligning Pathology Assessment in a Learner-Cantered Undergraduate Medical Curriculum
Introduction: The Bond Medical Program delivers pathology in the preclinical years through interactive learning. Assessment for learning demandsfit-for-purpose assessmentthat aligns with the curriculum. In Year 2 of the...
Deficit Syndrome of Schizophrenia: Assuaging by Norepinephrine Reuptake Inhibitor
Objective: Despite advances made in treating the positive symptoms of schizophrenia, treatment of negative symptoms remains an unmet therapeutic need. Reboxetine is a norepinephrine reuptake inhibitor (NRI). Objective of...
Metabolic Mechanisms Underlying Low Circulating Lactate and Pyruvate in Subjects With Alzheimer’s Disease
Subjects with Alzheimer’s disease (AD) may have low levels of circulating lactate and pyruvate but normal plasma ketone bodies (KBs, β-hydroxybutyrate and acetoacetate). In this paper, we point out the underlying mechani...
International Education Collaboration Using Social Media in Teaching and Learning Pain Management
All health-related professionals encounter patients with pain throughout their career. Pain is also a culturally moderated phenomenon. This project describes a journey of using social media to enhance the learning experi...
Sentinel Ganglion
Sentinel lymph node technique is well known among physicians who treat breast cancer or melanoma but is roll in colorectal cancer is still under investigations. We made an analysis of this simple technique th...