Outcome of acute vasculopathies in children- A case control study
Journal Title: MedPulse -International Medical Journal - Year 2014, Vol 1, Issue 11
Abstract
Introduction: Acute vasculopathy is still regarded as a rare event in childhood and therefore knowledge of diagnostics, therapy and prophylaxis is limited among general pediatricians. Besides the greater awareness, an objective increase in childhood thrombosis is due to the medical progress in the treatment of critically ill patients. The present study is an attempt to evaluate etiology, risk factors, clinical presentation and outcome of acute vasculopathy in children. It also intends to measure outcome of acute vasculopathies with or without chronic underlying disorder. Objective: To study clinical presentation and difference in outcome in cases of acute vasculopathies in children with and without underlying disorder. Study Design: Case control study. Study Period: 1 Year. Study Settings: Govt. Medical College and Hospital, Nagpur, Maharashtra, India. Data Collection: Pediatric Patients visiting Out-Patient, admitted in Pediatric Wards and Pediatric Intensive Care Units (PICU). Data Entry: was done by Microsoft Excel 1997-2003 Software. Statistical analysis: was carried out by STATA VERSION 0.8. Results: Hemoglobin <10 gm/dl was an independent risk factor for acute vasculopathy. There was strong co-relation between low GCS (Glasgo Coma Scale) ≤8 and MR (Modified Rankin) Scale ≥3 with poor outcome. Survival without Sequele was more in case group and survival with sequele was more in control group. Among controls coagulopathy and sickle cell disease are common predisposing factors. This study concludes poor outcome in children with acute vasculopathy who have chronic underlying disorder.
Authors and Affiliations
N H Lonikar, K G Rathod, A K Niswade, Ubaid UR Raheman
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