Outcome of patients subjected to short course chemotherapy (DOTS) under RNTCP at tertiary care institute
Journal Title: MedPulse -International Medical Journal - Year 2014, Vol 1, Issue 9
Abstract
Introduction: Tuberculosis is leading infectious cause of death worldwide being responsible for 3-million deaths annually, with 6% of all deaths worldwide attributable to tuberculosis. About 95% of tuberculosis cases and 98% of all deaths occur in poor developing countries. Present study was carried out to study outcome of newly diagnosed cases of Tuberculosis subjected to short course chemotherapy regimen under DOTS. Aims and Objectives: To study the outcome of patients subjected to short course chemotherapy (DOTS) under RNTCP at tertiary care institute. Material and Method: All the newly diagnosed cases of pulmonary and extra pulmonary tuberculosis attending OPD/IPD of Govt. Medical College Nanded and residing in area under coverage of RNTCP centre of GMC Nanded were included in this study. Name, age, sex, address, occupation, income, number of family members, presenting complaints in chronological order, past history, personal history, through general and systemic examinations, investigations were carried out and the findings were recorded. All the standard definitions defined by Central TB division of Directorate General of Health Services were used. All the patients were followed up regularly and outcome was recorded. Results: Out of 221 patients, 126 were of pulmonary tuberculosis and 95 were suffering from extra pulmonary tuberculosis. Out of all sputum positive cases 84.54% of patients were converted to sputum negative status after two months of Intensive phase. 66.66% patients were cured after DOTS. 19.04% cases of pulmonary tuberculosis and 90.52% of extra pulmonary tuberculosis had completed the treatment. Success Rate (Success Rate = cure + treatment completed) for pulmonary tuberculosis was found to be 85.70% and failure rate among smear positive was 2.08%. Success rate for extra pulmonary Tuberculosis was found to be 90.52%. Thus overall Success Rate for PTB and EPTB was found to be 87.78%. Conclusion: Overall success rate of DOTS amongst PTB and EPTB was found to be 87.78%. The treatment effectiveness of DOTS is evident from smear conversion rate at 2-3 months and success rate (cure rate >85%) both above satisfactory mark by RNTCP guidelines.
Authors and Affiliations
Sanjiv Zangde, Anjali Deshmukh
Keywords
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