OVERVIEW ON RECENT EXTRACTION TECHNIQUES IN BIOANALYSIS
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2016, Vol 7, Issue 2
Abstract
This review is focused on Bioanalytical Strategies and gives update on the Bioanalytical Tools in Drug Discovery. The method used for sample collection, sample preparation. In sample preparation liquid-liquid extraction [LLE], solid phase extraction [SPE] and protein precipitation is traditional method. The recent methods are salting out assisted liquid extraction, protein precipitation plate and development in solid phase extraction in that molecularly imprinted polymer SPE, dispersive SPE, disposable pipette extraction, micro extraction by packed solvent, solid phase micro extraction, stir bar Sportive extraction and on line solid phase extraction ,this developed Bioanalytical methods applied various purposes such as pharmacokinetic studies, pharmacodynamic studies and comparative clinical studies.
Authors and Affiliations
K. V. Reddy , Ashish Yachawad
FORMULATION DEVELOPMENT OF IRBESARTAN (POORLY WATER-SOLUBLE DRUG) IMMEDIATE RELEASE TABLETS
The aim of the present study is to increase the solubility of poorly water soluble drug Irbesartan by using surfactants and formulating into immediate release tablets by using super disintegrants. Surfactants such as sod...
ANTIBACTERIAL STUDIES ON BENINCASA HISPIDA AND NIGELLA SATIVA OIL
Fixed oil of seeds of Benincasa hispida and Nigella sativa was found active against various resistant pathogens of both gram positive and gram negative bacteria. The maximum zone of inhibition was observed against S.aure...
STUDY OF KRIMIGHNA EFFECT OF NIMBA (AZADIRACTA INDICA A.JUSS.) PATRA AS RAKSHOGHNA DHOOPAN BY CULTURE AND SENSITIVITY METHOD W.S.R. TO PYOGENIC BACTERIA
Nimbapatra (Azadiracta indica A.juss) is described as Krimighna in Ayurvedic literature. In the present study Pyogenic bacteria i.e. Staphylococcus aureus and Streptococcus pyogenus were grown on artificial media in labo...
IN VITRO CYTOTOXIC EFFECT OF METHANOLIC CRUDE EXTRACTS OF TERMINALIA CHEBULA
The aim of this work is to observe invitro cytotoxic effect of methanolic crude extracts of Terminalia chebula (Family: Combretaceae). The bark of Terminalia chebula were soaked with methanol and then methanolic crude ex...
TRACHYSPERMUM AMMI (AJWAIN): A COMPREHENSIVE REVIEW
The use of plants as medicine is as old as human civilization. People of all ages in both developing and developed countries use plants in an attempt to cure various diseases and to get relief from physical sufferings. N...