Oxidative Cleavage of Glycine with N-Chlorobenzimidazole in Aqueous Acetic Acid Medium
Journal Title: IOSR Journal of Applied Chemistry (IOSR-JAC) - Year 2018, Vol 11, Issue 4
Abstract
The oxidative cleavage of glycine with N-chlorobenzimidazole (CBI) has been studied in aqueous acetic acid medium. The rate shows first order dependence each on [CBI] and [glycine] and inverse first order on [H+ ]. The rate of the oxidation increases with decrease in dielectric constant of solvent medium indicating ion-dipole interaction. Polymerization was not observed when acrylonitrile is added to the reaction mixture. The kinetic runs were carried out at four different temperatures and thermodynamic parameters have been evaluated. Addition of benzimidazole retards the rate. The rate of reaction is not influenced by the addition of electrolyte like sodium perchlorate. A mechanism in consistent with the kinetic data has been proposed.
Authors and Affiliations
K. Rama krishnan, B. Ram kumar
Keywords
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