Paroxysmal Nocturnal Hemoglobinuria Causing Budd Chiari Syndrome - A Rare Case Report
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 4
Abstract
Abstract: Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired disorder of hematopoietic stem cells characterized by hemolytic anemia, marrow failure, and a high incidence of life-threatening thrombosis. PNH can be diagnosed with a single blood test and has a poor prognosis if untreated. It is an important cause of intra-abdominal thrombosis and therapy with the anti-complement drug, eculizumab, is very effective. Eculizumab usually prevents further thrombotic complications, thus emphasizing, that early diagnosis is critical. We report a case of a young female who presented with Budd Chiari syndrome and pancytopenia and on further evaluation turned out to be a case of PNH. Keywords:paroxysmal nocturnal hemglobinuria, hemolytic anemia, thrombosis, Budd Chiari Syndrome
Authors and Affiliations
Sarabjot Kaur, Narendra Meena, Ravinder Garg, Sumit Pal Singh Chawla, Vidhi Singla
Keywords
Related Articles
- EP ID EP372108
- DOI -
- Views 42
- Downloads 0
A Cross Sectional Study on Menstrual Hygeine, Pattern & Other Menstrual Problems among Adolescent School Going Girls
Abstract: Adolescence is the period of rapid physical growth, psychological and social changes. An understanding of the physiology of puberty and menarche is essential for all adolescent girls so that they can acquire ac...
Cost effectiveness of screening tests for UTI in CKD population
UTI is the most common hospital acquired infections, accounting for 35% in hospitalized patients. Early diagnosis and prompt treatment of UTI in CKD patients is necessary to prevent grievous complications. The objective...
Study of 100 Case of Chronic Fissure in Ano for Comparing Between Anal Dilatation and Lateral Anal Sphincterotomy
Anal fissure is common cause of anal pain. Exact etiology of anal fissure is not known, but it is commonly seen due to constipation and hypertonic anal sphincteric conditions. Studies on the method of treatment of chron...
Study of Lipid Profile and Glycemic Control in Type 2 Diabetes Mellitus Patients with and without Non Alcoholic Fatty Liver Disease as diagnosed by Ultrasonography
Non-alcoholic fatty liver disease (NAFLD) has emerged as the most common cause of chronic liver disease worldwide. NAFLD is strongly associated with T2DM and cardiovascular disease (CVD). It is characterized by insulin r...
Intima-Media Thickness of Common Carotid Artery in Individuals with Impaired Fasting Glycemia in Comparison with Normal Healthy Adults by B-Mode Ultrasonography
Abstract: Impaired fasting glucose is an important risk factor for subsequent development of both diabetes mellitus and cardiovascular diseases. One of the complications of diabetes is acceleration of atherosclerosis in...