PATHOPHYSIOLOGICAL BASIS OF HAEMATOLOGICAL PROFILE OF DENGUE FEVER.
Journal Title: International Journal of Basic and Applied Physiology - Year 2016, Vol 5, Issue 1
Abstract
Background: Dengue is a self-limiting acute viral disease characterized by fever, muscle & joint pains, headache, rash, nausea & vomiting. It is transmitted by female mosquitoes mainly of the species Aedes aegypti and less by, Aedes albopictus. Dengue virus infection may be asymptomatic or may cause undifferentiated febrile illness (viral syndrome), dengue fever (DF), or dengue haemorrhagic fever (DHF) including dengue shock syndrome (DSS). Objectives: To evaluate the haematological profile for early clinical diagnosis & prompt management. Methods: Study was done in 100 patients diagnosed as dengue fever. IgM positive or NS 1 positive patients of dengue fever with age group between 18-60 years patients were taken. Parameters of haematological profile was taken in all patients. Result: Out of 100 patients, 22% had mild thrombocytopenia, 47% had moderate thrombocytopenia and 29% had severe thrombocytopenia. Overall 98% of patients had thrombocytopenia. About haematocrit, 36% patients having haematocrit below 40% and 49 % of patients having haematocrit between 40 to 45%, and only 15 % of patients having haematocrit above 45%. Leucopenia was seen in 29 % of patients. Conclusion: Thrombocytopenia was key finding in our study & other associated findings included leucopenia, rise in haematocrit
Authors and Affiliations
Sonal A. Chavda, Sudha Parmar, R. S. Trivedi
Keywords
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