Pattern of palpable breast lesions on fine needle aspiration cytology: a retrospective and prospective analysis of 1,000 cases
Journal Title: International Journal of Medical Science and Public Health - Year 2016, Vol 5, Issue 1
Abstract
Background: In both developed and developing countries, breast lumps comprise a considerable amount of surgical cases in women. Objective: To look the frequency distribution of various breast lesions on fine needle aspiration (FNA). Materials and Methods: The 1,000 patients who presented with palpable breast lump, age group including 16–60 years and both sexes, were included in the study. Frequency distribution of various breast lesions with respect to age and sex was studied. Result: The majority [98% ( N = 980)] of patients were female subjects and rest [2% ( N = 20)] male subjects. With reference to the age, maximum [66.6% ( N = 666)] patients were between second and third decades and rest [33.4% ( N = 334)] in fourth and fifth decades. Benign breast lesions contributed to majority of the cases [57.3% ( N = 573)], malignant breast lesions to 26.8% ( N = 268) of the cases, and the inflammatory lesions to 15.9% ( N = 159) of the cases. Of the 268 (26.8%) malignant breast lesions, 38% ( N = 102) of cases were aged between 41 and 50 years, 33% ( N = 88) of cases 51–60 years, and 29% ( N = 78) of cases 31–40 years. In malignant breast lumps, majority are duct carcinoma NOS ( N = 229), while in benign breast disease, fibroadenoma are found to be the commonest one. Cytology grading of malignant lesion showed maximum cases with grade II, followed by grades I and III. Conclusion: With experienced hands, fine needle aspiration (FNA) cytology is a safe, cost-effective, and reliable tech - nique for preoperative evaluation of palpable breast lumps. FNA features are more informative when combined with clinical and radiological findings. Fibroadenoma forms the major bulk of benign breast lesions, followed by duct carcinoma. Epithelioid cells when seen in inflammatory breast FNA smears, tuberculosis must be ruled out. In India, breast carcinoma is noted in younger patients when compared with western countries. Grading of breast carcinomas must be done on FNA smears for selecting the neoadjuvant therapy. Clinical breast examination and mammography screening in female sub - jects should be encouraged in developing countries from the third decade onward for early detection of breast carcinoma.
Authors and Affiliations
Shikha Ghanghoria, Swati Soni, Harshul Patidar, Khushboo Likhar
Keywords
Related Articles
- EP ID EP133224
- DOI 10.5455/ijmsph.2016.2306201524
- Views 65
- Downloads 0
Indian Medical Pharmacologists Association: New Beginning
Pharmacology is a rapidly evolving field. In India, it all started when the Association of Physiologists and Pharmacologists (APPI) was formed and the budding field of pharmacology had its first foot in independent...
A comparative study of intrathecal 0.5% isobaric levobupivacaine with 0.5% hyperbaric bupivacaine for vaginal hysterectomy
Background: Hyperbaric bupivacaine (0.5%) is frequently used in vaginal hysterectomy for spinal anesthesia due to longer duration and reliable motor and sensory blockade. However, the risk of cardiac and central nervous...
Quality assessment of facilities available at Primary Health Care centres in Rajkot district: A Cross Sectional Study
Background: Primary health care through the setup of sub centre and PHCs build up the base of the health of community. Primary health care includes not only the curative care for the diseases, but also...
Assessment of serum uric acid levels in Type 2 diabetes mellitus patients
Background: Diabetes mellitus is a metabolic disorder of carbohydrate metabolism, producing hyperglycemia and is affected by factors like insulin resistance. Hyperglycemia can produce reactive oxygen species or free radi...
Socio-demographic profile and associated risk factors in cancer patients attending the Oncology OPD of a tertiary care teaching hospital in Western Maharashtra, India
Background: Cancer has become one of the ten leading causes of deaths in India. The common sites of cancer have close association with certain risk factors. The leading sites of cancer have varied in different geogr...