Patterns of Distant Failure in Carcinoma Cervix- A Regional Cancer Centre Experience
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 10
Abstract
Background: Cervical cancer is the most common malignancy among Indian females and is the leading cause of death. Patients with locally advanced cervical cancer after concurrent chemo radiation distant failure occur in many cases. Aim: To study the age distribution, clinical profile, sites, patterns, & duration of development distant failure in carcinoma cervix after completion of primary treatment. Materials: Retrospective study from the treatment records of patients of carcinoma cervix undergoing treatment at AHRCC. From January 2013 to June 2016, 91 patients of metastatic carcinoma cervix were selected & analysed retrospectively. Result: Majority of patients were from 5th and 6th decade followed by 7th decade. Most of them were in stage IIIB followed by stage II. Squamous cell histology was the most common entity. Commonly presented with non-regional nodal metastases out of which para-aortic lymph node metastases predominates. Following nodal metastases lungs was the second most site. Liver, bone and brain metastases were also seen. Most of the patients presented with metastasis within a period of 2 years from initial treatment time. Conclusion: Distant failure in carcinoma cervix depends upon the initial stage, age of presentation and histological findings. Though cervical carcinoma frequently spreads to the para-aortic nodes, lungs, liver and other uncommon sites are also reported. It necessitates a stringent follow up during period of first two years
Authors and Affiliations
Dr Sanjukta Padhi
Keywords
Related Articles
- EP ID EP214581
- DOI -
- Views 83
- Downloads 0
A study to compare the efficacy, safety & economy of oral iron chelators in patients with Thalassaemia major
Background: Thalassemia is an inherited impairment of hemoglobin production, in which there is partial or complete failure to synthesize a specific type of globin chain. It is characterized by ineffective erythropoesis a...
The Clinical Outcomes of Local Steroid Injection Plus Conservative Management and Conservative Management Alone in Chronic Low Back Pain Due to Myofascial Pain Syndrome
Background: Myofascial Pain Syndrome (MPS) is defined as a regional pain syndrome characterised by muscle pain caused by myofascial trigger points (MTrPs). The prevalence of MPS among chronic back pain patients is high....
Oral Midazolam and Ketamine as Premedicants in Children- A Randomized Open Label Single Centre Study
Operation theatre and emergency room environment induces fears in a child which include those due to separation from parents, of pain, fear of the unknown and unfamiliar environment and fear due to loss of control and pr...
Dry Eye and Corneal Sensitivity in Patients with Type 2 Diabetes Mellitus
Background: Ocular surface disorders in diabetes mellitus have gained significant attention in recent years, as there is increased reporting of the association of dry eye and diminished corneal sensitivity in these patie...
Determination of Optimal Dose of Intrathecal Dexmedetomidine
Role of dexmedetomidine as adjuvant to intrathecal local anaesthetics is being increasingly described in the literature. This prospective, double blind, randomised study evaluated various doses of dexmedetomidine with an...