Perinatal outcome in relation with laboratory findings in pregnancy induced hypertension(PIH)
Journal Title: International Journal of Clinical Biochemistry and Research - Year 2016, Vol 3, Issue 1
Abstract
Background: Perinatal mortality is an important indicator of the status of maternal and child health, the conditions of obstetric care and the level of economic development of a community. The perinatal mortality rate (PMR) reflects both the characteristics of reproductive health and the quality of antenatal care, delivery, and newborn care. Objective: To find out the corelation between laboratory parameters with perinatal outcomes in PIH cases. Method: 320 patients having an average systolic blood pressure ≥ 140 mm hg and/or diastolic blood pressure ≥ 90 mm Hg were included in the study and biochemistry parameters like serum AST, ALT analysed by UV kinetic, LDH by UV kinetic IFCC, Uric acid by modified Trinder’s method and calcium by arsenazo III methods, were measured by Xl 300 autoanalyzer. Result: In our study overall incidence of PIH was 14.3 %. Maternal death occurred in 09 cases(2.8%). Perinatal mortality occurred in 86(23.3%) with 57(17.8%) Stillbirth and 29(9.0%) Neonatal deaths. Low birthweight<2.5Kg 73(84.8%) was the common complication observed followed by prematurity 64(74.4%) and IUGR 40(46.5%) leading to perinatal deaths. PMR increased as the BP increased. It was 14.9% for BP 140/90 to 149/94, to 57.3 % at BP >160/110 and above (Table 2). Perinatal death increased significantly in PIH women with increased levels of serum AST, ALT, uric acid, LDH and with a significant decrease in serum calcium levels. Perinatal death occurred in 63(73%) cases with Uric acid >6.0 mg/dl, 48(55.8%) in cases with > 600U/l LDH and in 48(55.8%) cases with < 8.0 mg/dl Calcium. Conclusion: A positive correlation has been made out between serum AST, ALT, uric acid, LDH, calcium and perinatal deaths in relation to the severity of PIH and these may be useful markers and diagnostic tools for predicting the progression of PIH
Authors and Affiliations
Liggy Andrews, Haridas Namboothiri, Smruti Vaishnav
Keywords
Related Articles
- EP ID EP242190
- DOI -
- Views 113
- Downloads 0
Serum 25- Hydroxy Vitamin D levels in Type 2 Diabetes Mellitus- A Comparative study
Background: Type 2 diabetes mellitus (DM) is a disease of impaired carbohydrate metabolism. Vitamin D deiciency and diabetes mellitus are two common conditions and they are widely prevalent across all ages, races, geogra...
A study on adenosine deaminase activity in pleural effusion of tuberculous and non tuberculous origin
Introduction Accumulation of fluid in the pleural space that exceeds the physiological amount is defined as pleural effusion Pleural effusion can be either transudative or exudative The exudative pleural effusion is pred...
Distribution of subclinical thyroid disease and other primary thyroid disorders in a tertiary care center
Background: Thyroid dysfunctions are common endocrine problems. They account for a considerable morbidity and mortality. Subclinical thyroid diseases especially subclinical hypothyroidism is a common clinical entity that...
Usefulness of serum gamma glutamyl transferase in assessing severity of preeclampsia
Introduction: Pre-eclampsia is a multisystem disorder, unique to pregnant women after twenty weeks of gestation. In India the incidence of pre-eclampsia is reported to be 8-10% of the pregnancy. It contributes significan...
A comparative study of electrolyte imbalances in controlled and uncontrolled diabetes mellitus
Objective: Our aim is to study the pattern of electrolyte imbalances in patients with diabetes mellitus and to compare the results among controlled and uncontrolled diabetes mellitus and also to find out the correlation...