Periodontal Management Of Amlodipine-Induced gingival Over Growth: A 2 Years Follow-Up Case Report
Journal Title: Journal of Medical and Dental Science Research (Quest Journals JMDSR) - Year 2018, Vol 5, Issue 1
Abstract
Gingival overgrowth (GO) is one of the most important clinical features of gingival pathology. It has been found to be associated with the use of anticonvulsants; phenytoin, anti-hypertensives; calcium channel blockers and immunosuppressants; cyclosporine. Nifedepine was found to cause gingival overgrowth with an incidence ranging from 15-85%. However, Amlodipine new 3rd generation calcium channels blocker, has also been found to exhibit this adverse effect with very few cases reported till date. The effect of the dose of amlodepine on the severity of gingival enlargement needs to be assessed. This paper presents a case report of an 63 years old female with gingival over-growth as a side effect of a 10 mg per day therapy with amlodepine. A brief review on the pathogenesis of this condition, commonly associated with etiological mechanisms and sequence of periodontal therapy rendered have also been included. Gingival enlargement continues to be a predominant side effect of calcium channel blocker. The accentuated gingival contours accumulate plaque leading to the destruction of the underlying periodontium. Dental professionals need to identify and then guide the patient to seek necessary medical intervention.
Authors and Affiliations
Houda ElGhoulbzouri, Samir Er-raji, OumKeltoum Ennibi
Keywords
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