Pexophagy in Penicillin G Secretion by Penicillium chrysogenum PQ-96
Journal Title: Polish Journal of Microbiology - Year 2016, Vol 65, Issue 3
Abstract
Penicillin G oversecretion by Penicillium chrysogenum PQ-96 is associated with a strictly adjusted cellular organization of the mature and senescent mycelial cells. Abundant vacuolar phagy and extended cellular vacuolization combined with vacuolar budding resulting in the formation of vacuolar vesicles that fuse with the cell membrane are the most important characteristic features of those cells. We suggest as follows: if the peroxisomes are integrated into vacuoles, the penicillin G formed in peroxisomes might be transferred to vacuoles and later secreted out of the cells by an exocytosis process. The peroxisomal cells of the mycelium are privileged in penicillin G secretion.
Authors and Affiliations
Wieslaw Kurzątkowski, Anita Gębska-Kuczerowska
Keywords
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- EP ID EP81131
- DOI 10.5604/17331331.1215616
- Views 69
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