Phaleria macrocarpa (Boerl.) Scheff Fruit: A Potential Source of Natural Antioxidant
Journal Title: Pharmacology and Clinical Pharmacy Research - Year 2018, Vol 3, Issue 1
Abstract
Phaleria macrocarpa (Scheff.) Boerl is originated from Papua Island, Indonesia. There have been only limited attempts to explore the biological properties of this plant in relation to their medicinal use. This study aimed to examine antioxidant activity of P. macrocarpa fruit. Extraction of pericarp and mesocarp of P. macrocarpa were performed using soxhlet method with ethyl acetate as the solvent. Antioxidant activity was characterized in various in vitro model systems, including DPPH and ferric reducing antioxidant assay. We found that the highest amount of phenolic compounds and flavonoids were found in the pericarp (58.3±0.07 mg/g DW and 127.8±1.08 mg/g DW, respectively). The results showed that pericarp had higher antioxidant activity (IC50= 122.4±1.14 μg/ml) compared to mesocarp (IC50=175.48 ±1.75 μg/ml). In conclusion, the result of this study indicated the possible application of P. macrocarpa as a source of natural antioxidant compound
Authors and Affiliations
Rudi Hendra, Yuli Haryani
Sterility Status of Reusable Medical Instruments in Intermediate Care Rooms at Dr. Hasan Sadikin General Hospital Bandung
Hospital-acquired infection has become serious issue during previous decades. In Indonesia, the prevalence of nosocomial infection reached almost 10% of total patients encounter. The objective of this study was to invest...
Anti-proliferative Activity of Crotalaria pallida Aiton on MCF-7 Breast Cancer Cells
Crotalaria pallida Aiton (C. pallida Aiton) is empirically used as dietary supplement to treat cancer by the people of North Sulawesi. However, its scientific pharmacology activity has not been explored yet. Therefore, t...
Antioxidant Activity of Ethanol Extract of Polygonum pulchrum Blume
The use of antioxidants from natural resources has attracted increasing interest. One of the plant that was empirically used as an antioxidant dietary supplement was Polygonum pulchrum Blume (P. pulchrum Blume). This stu...
The Inhibitory Activity on the Rate of Prostaglandin Production by Zingiber officinale var. Rubrum
Red ginger (Zingiber officinale var. Rubrum) is widely used by Indonesian as a traditional medicine to treat inflammation. The aim of this research was to provide information regarding the inhibitory activity of red ging...
Local Hemostatic Activity of Psidium guajava Leaves in Swiss Webster Mice
Psidium guajava (P. guajava) leaves have been empirically used to stop bleeding. Tannin, one of this plant’s secondary metabolites, may contribute to this activity. However, information regarding its pharmacologicy activ...