Pharmaceutical aspects of photometric analysis of drugs
Journal Title: Фармацевтичний журнал - Year 2014, Vol 4, Issue 4
Abstract
Problems of improving ways to assess the quality of medicines currently apply to all sections of the pharmacopoeia analysis, due to the revision of traditional approaches to identifying, testing for purity, the determination of the pharmacologically active substance or substances in the substance, dosage forms and, most importantly, in multicomponent medicinal compounds. The aim of this work was to study the literature data concerning pharmacopoeia analysis of pharmacologically active substances in the substance and dosage forms using the method of spectrophotometry. In this paper we have used the methods of search, analysis and compilation of information sources on the analysis of pharmaceutical drugs using spectrophotometry. It has been carried out analysis the published data on the use of electronic spectrophotometry to investigate the quality of substances and dosage forms. Justification of the choice of optimal quality control methods with the requirements of State Standard and State Pharmacopeia of Ukraine also due to the method of statistical processing of the analysis results. Certainly, better statistical analysis is achieved by selecting the optimum experimental conditions (wavelength, consistency). It has been given recommendations for use of solvents for identification and quantification of drugs. As well as the choice of the optimal methods of quality control of medicines in accordance with IUPAC and State Pharmacopeia of Ukraine.
Authors and Affiliations
O. I. Panasenko, V. P. Buryak, I. A. Iurchenko, I. M. Keytlin, Yu. V. Tymoshyk
Keywords
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