PHARMACEUTICAL VALIDATION & PROCESS CONCEPTUALISATION OF ANCIENT INDIAN CALCIUM PREPARATION: SHANKHA BHASMA
Journal Title: International Journal of Pharmaceutical Sciences and Research (IJPSR) - Year 2019, Vol 10, Issue 10
Abstract
In the present study, the pharmaceutical and therapeutic dimensions of Shankha Bhasma (Classical Ayurvedic marine medicine) is explored as a substitute for calcium supplements available in the market. Shankha Bhasma was prepared & standardized by Ayurvedic pharmaceutical procedure accordingly in Rasa Tarangini (a classical 20th-century book on Ayurvedic pharmaceutical medicine). Conch shell (Shankha) was subjected to bio-fomentation (Swedana) in a precise heating container (Dolayantra) containing lemon juice for 12 h. Further, triturated with Aloe vera juice (Kumari Swarasa) for bio-impregnation (Bhavana) and subjected to the controlled quantum of heat (Marana) in the sealed earthen saucer at 700 °C for 2 h, till all the classical and contemporary quality parameters about bio-metallic medicinal powder (Bhasma) was assured. On completion, average weight loss was 17-21%. The final product obtained was calcite form of CaCO3 and calcium oxide hydrate (CaO.H2O). This paper explores scientific evidence of ancient Ayurvedic pharmaceutical procedures in terms of bio-fomentation, bio-impregnation, transfer mechanism of quantum of heat along with the principles of fluid mechanics & thermodynamics.
Authors and Affiliations
V. Meena et al.
Keywords
Related Articles
- EP ID EP656904
- DOI 10.13040/IJPSR.0975-8232.10(10).4724-30
- Views 77
- Downloads 0
HYDROXYAPATITE AND Zn-HYDROXYAPATITE SYNTHESIS USING CALCIUM FROM LAKE MANINJAU PENSI SHELLS AND RESISTANCE TEST ON BACTERIA
HAp and Zn-HAp Synthesis with several concentrations of Zn (5%, 10%, 15%, and 20%) w/w using Ca precursor from Maninjau Lake pensi shells was done with the sol-gel method. XRF for three hours obtained 96.525% Ca content...
SYNTHESIS OF NEFOPAM ANALOGUES AND CHARACTERISATION
Modified Benzoxazocine moiety of Nefopam with N-Protected-ethanolamine, fluorobenzene benzylbromide, 2,3-dimethyl-benzene, naphthalene, fluro-naphthalene. In these modification Friedel Craft alkylation plays vital role w...
FORMULATION AND CHARACTERIZATION OF NUTRACEUTICAL NECTAR BASED ON ORANGE JUICE AND GREEN TEA
Green tea represents a popular beverage worldwide due to its high polyphenol and antioxidant activity. It is commonly brewed along with vitamin C source which plays a positive role in maintaining its antioxidant potentia...
PHYTOCHEMICAL ANALYSIS AND IN-VITRO ANTICANCER ACTIVITY OF DURANTA ERECTA L. (VERBENACEAE)
The aim of the present work is the evaluation of anticancer activity of Duranta erecta L. stem extracts and also an investigation of the phytoconstituents from the different extracts of the plant. Chloroform, ethyl aceta...
FLOATING ORAL IN-SITU GEL, A COMPREHENSIVE APPROACH OF GASTRO-RETENTIVE DRUG DELIVERY SYSTEM: A REVIEW
Conventional oral dosage forms posses low bioavailability problems due to their rapid gastric transition from the stomach. Especially some drug which is less soluble in alkaline pH and producing local action in the stoma...