Pharmacognostical and Pharmaceutical Evaluation of Devdarvyadi Vati-A Compound Ayurvedic Formulation
Journal Title: Scholars Academic Journal of Pharmacy - Year 2015, Vol 4, Issue 3
Abstract
Childhood period is a crucial stage for rapid growth and development. All the phases of growth and development are easily affected by unfavorable conditions like use of contaminated foods and water, faulty food habits etc. In day to day practice, pediatricians come across with good number of patients suffering from diseases related to gastrointestinal tract i.e. loss of appetite, abdominal pain, vomiting, bowel disturbances (diarrhea, constipation) etc. If these problems are ignored, they lead to malnutrition and its complications. The changed lifestyle is responsible forvitiation of Agni, improper Agni especially Mandagni results in Grahani Dosha, which is a precursor stage of malabsoption syndrome. Devdarvyadi Churna is indicated in such condition. Devdarvyadi Churna converted into Vati form due to easy palatability in pediatrics patients and drugs were selected in the present study. The present work was carried out to standardize the finished product Devdarvyadi Vati to conform its identity, quality and purity. The pharmacognostical work reveals that presence of lignified fibers of Devadaru (Cedrusdeodara (Roxb.) Loud),starch with oiliores in content of Vacha (Acoruscalamus Linn.), starch grain in Musta(Cyperusrotundus Linn.), starch with oiliores in contentin Shunthi (Zingiberofficinale Roscoe.)prismatic crystal of Ativisha(Aconitum heterophyllum Wall. ex Royal), epicarpe cells of Haritaki (Terminalia chebula Retz.) were observed microscopically. Organoleptic features of coarse powder made out of the crude drugs were within the standard range as per mention in classic. The pH value ofDevdarvyadiVatiis4, Water soluble extract is 11.07%w/w, Loss on drying is 5.73 %w/wand High Performance Thin Layer Chromatography (HPTLC) at 254nm and 366nm resulted into 5 and 6 spots respectively.. Keywords: Grahani Dosha, Devdarvyadi Vati, HPTLC, Pharmacognosy, Pharmaceutics.
Authors and Affiliations
Vhora Maleka, Patel KS, Harisha CR, Rajagopala S, Shukla VJ
Keywords
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