Phenthoate 50% EC Toxicity and Its Impact on Aminotransferases of Freshwater Fish Catla (Gibelion catla)
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2018, Vol 13, Issue 1
Abstract
The toxicity of commercial grade Phenthoate 50% EC. to the freshwater fish Catla (Gibelion catla) using static system, LC50 values were determined as 14.2, 13.0, 12.0 and 7.0 ppm respectively. The fish were exposed to Lethal and Sub-lethal concentrations (1/10th of static 96 h LC50 value) of the pesticide for 96 h and the biochemical changes of amino transferases, Aspartate aminotransferase (SGOT/AST) and Alanine aminotransferase (SGPT/ALT) were estimated in the test fish. Increased activities of AST and ALT in different tissues of brain, liver, muscle, gill and kidney in the test fish suggest either increased operation of transamination or increased synthesis of amino acids from other sources like glucose or fatty acids during Phenthoate 50% EC intoxication, The changes in lethal exposure were more prominent compared to sub-lethal exposure fish. These changes were attributed to the intoxication of the test toxicant Phenthoate 50% EC.
Authors and Affiliations
T. Kusuma Kumari, Mariyadasu. P
Keywords
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- DOI 10.9790/3008-1301040609
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