Physiological and biochemical processes in the organisms of rats that were fed with different amounts of germanium citrate
Journal Title: Біологія тварин - Year 2015, Vol 17, Issue 2
Abstract
Organic germanium compounds are characterized by a wide spectrum of effect on the organisms of people and animals and are used as a food supplement to enhance the immunological organism reactivity. However, using of the toxic inorganic forms as precursors for obtaining organic germanium compounds by chemical synthesis indicates the urgency of searching for the alternative ways to get them. This article presents the results of the study of the influence of different amounts of germanium citrate, which was obtained by electric impulse nanotechnology method, onto the physiological processes in rat organismto determine the optimal dose. The germanium citrate solutions with the concentrations of 10, 200, and 300 µg of Ge/L were used in the study. It was determined that feeding with germanium with the concentration of 10 µg of Ge/L did not show significant changes of the studied parameters. While an elevated concentration of hemoglobin, circulating immune complexes, and average weight molecules were observed in the blood of the rats, which were fed with germanium citrate with the concentrations of 200 and 300 µg of Ge/L. Such changes may indicate the immunomodulatory properties of the germanium citrate. Probable decrease in the concentration of the lipid hydroperoxides and TBA-active products in the blood of the animals, which were fed with the germanium citrate with the concentrations of 200 and 300 µg of Ge/L of water, was also found out. More effective physiological influence of the germanium onto the peroxidation processes was noticed in case of feeding its citrate with the concentrations of 200 and 300 µg of Ge/L. So feeding with the germanium citrate, produced with the help of the nanotechnology method, improves the immunological indicators and reduces the intensity of the lipid peroxidation of the infant rats.
Authors and Affiliations
O. P. Dolaychuk, R. S. Fedoruk, I. I. Kovalchuk, S. I. Kropyvka
Keywords
Related Articles
- EP ID EP349737
- DOI 10.15407/animbiol17.02.050
- Views 84
- Downloads 0
The content of certain heavy metals in tissues and products of honey-bees under the condition of their feeding with native soy flour adding chloride and aquanano chrome citrate
The influence of feeding with native soy flour, adding chloride and aquanano chrome citrate, on the content of chrome, zink, cuprum, ferrum, cadmium, and plumbum in the tissues of a head, thorax, abdomen and the whole bo...
Histological structure of separate internal organs of piglets at application of probiotic feed additive
The aim of the test was to study the influence of probiotic feed additive in doses recommended by the producer and duration of application on the histological structure of separate internal organs of piglets. The product...
Maximal oxidative capacity of mitochondria in lymphoma NK/Ly with methyl esters of energetic substrates
The processes of respiration and oxidative phosphorylation in mitochondria are significantly determined by the transport of exogenous substrates through the plasma membrane. Methyl esters of the substrates of Krebs cycle...
Influence of feed additive “Humilid” on protein and amino acid metabolism indicators in broiler chickens of Cobb 500 cross
The article presents data on the effect of the feed additive “Humilid” the general biochemical parameters of blood and liver in broiler chickens of the Cobb 500 cross. It has been shown that chickens which received “Humi...
World experience and perspectives of genomic selection in dairy cattle
The review article is devoted to the world advances in genomic selection of cattle. Advances in animals genome sequencing track the inheritance of chromosomal fragments with low and high density chips to calculate the ge...