Phytochemical and Antifungal Activity of Nigeria Jatropha Multifudia Latex.
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 3
Abstract
Jatropha multifudia is an ornamental plant which is employed to cure various infections in traditional medicine. The phytochemical analysis of the latex in mg/100g revealed the presence of secondary metabolites with phenols having the greatest quantity of 14.32 ± 0.18, followed by tannins 8.16 ± 0.18, oxalates 6.03 ± 0.12 and phytates having least of 0.21 ± 0.10. Latex of this plant was analysed and screened against fungi (Trichoderma rubrum and Seleretion rolfsii ). The latex displayed potent antifungi activity against mentioned fungi, giving minimum inhibitory concentration as low as 0.5ml and this increases with maximum inhibitory concentration as high as 0.2ml. The latex extract shows significant zone of inhibition in dose dependent manner and the results are comparable with bentate (control). From this study, we conclude that the latex extract possess potent antifungal effects which may be further developed as alternative treatments for some fungicides.
Authors and Affiliations
Olagunju, Esther Olajumoke;, Oladipupo, Oluremi Adikat;, Abejoye, Abidemi Oluyinka;, Pharm. Badejo, Precious Olohigbe;, Ajala, Lawrence Olusegun;, Badejo Johannes Adedokun
Keywords
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- DOI 10.9790/3008-1103017779
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