PHYTOCHEMICAL AND ANTIOXIDANT PROPERTIES OF VARIOUS EXTRACTS OF MICHELIA CHAMPACA LEAVES
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2019, Vol 11, Issue 5
Abstract
Objective: To investigate and compare the phytochemicals, antioxidant activities of various crude extracts from fresh leaves of locally available plant Michelia champaca belonging to family Magnoliaceae. Methods: The present study was designed to perform preliminary phytochemical (qualitative and quantitative) analysis of various extracts. The crude extracts from the leaves of M. champaca were prepared using various organic solvents viz. Methanol (MCMET), Ethanol (MCETH), Hexane (MCHEX), and Chloroform (MCCHLO). In addition, total phenolic (TPC) and total flavonoid (TFC) contents of various extracts were also measured along with the evaluation of the antioxidant capacities using most widely accepted in vitro chemical tests such as DPPH and ABTS radical scavenging assay. Results: The methanolic extract of M. champaca showed the presence of maximum phytochemicals (12) when compared to other solvent extracts viz. Hexane (10), Ethanol (8) and Chloroform(7). The amount of phenolic and flavonoids present in solvents were in the order of Methanol>Hexane>Ethanol>Chloroform. The best antioxidant potential was found in the Methanol extract. The Methanolic extract exhibited an IC50 value of 72.03µg/ml (DPPH) and of 185.21µg/ml (ABTS), respectively for the two radical scavenging assays. Conclusion: Phytochemical analysis of M. champaca (leaves) various extracts showed good amounts of phenolic and flavonoid contents and also exhibited significant antioxidant activity. A positive linear correlation between the antioxidant activities and the total phenolic and flavonoid contents of the plant extracts was observed. Study revealed variations in such reported activities due to different organic extraction solvents used. In overall conclusion, Michelia champaca has good potential as a source of natural antioxidant for animal health and food industry and further relevant studies on similar lines would be worthwhile.
Authors and Affiliations
PUSHPA RUWALI, MAMTA ADHIKARI, SUBHANSHI SHARMA
Keywords
Related Articles
- EP ID EP565238
- DOI 10.22159/ijpps.2019v11i5.31745
- Views 141
- Downloads 0
IN VITRO MICROBIAL TIME-KILLING CURVE FOR NEWLY SYNTHESIZED AMINOACETYLENIC-2-MERCAPTOBENZOTHIAZOLE COMPOUND
Objective: To determine the time needed for killing different types of microorganisms by a newly synthesized 2-mercapto-1,3-benzothiazole derivative in comparison to ciprofloxacin and fluconazole.Methods: The minimum bac...
PRELIMINARY PRELIMINARY STUDY ON BLOOD PROFILE OF BLOOD PRESSURE AND VEGETABLE CONSUMPTION AMONG WOMEN IN THE ERA OF GERMAS IN CICANIR AND JATIPAMOR VILLAGES, MAJALENGKA REGENCY, WEST JAVA PROVINCE
Objective: To discover the profile of hypertension (HT) disease and consumption habit of vegetables among women in Cicanir and Jatipamor villages related to the program of Gerakan Masyarakat Hidup Sehat (GERMAS)/Healthy...
DESIGN AND DEVELOPMENT OF <em>NICOTIANA TABACUM</em> FILM USING FACTORIAL DESIGN
Objective: The objective of the present investigation was to develop and optimize Nicotiana tabacum oral dissolving films with optimized physicomechanical and chemical properties for improved patient compliance. Nicotian...
CALLUS INDUCTION, PHYTOCHEMICAL STUDIES AND ANTIBACTERIAL ACTIVITY OF DECALEPIS ARAYALPATHRA (JOSEPH AND CHANDRAS) VENTER
Objective: The aim of the present study was designed for the induction of callus from leaf explants of Decalepis arayalpathra (D. arayalpathra) and to analyse their phytochemical constituents and antibacterial activity.M...
LOADING OF CLARITHROMYCIN AND PACLITAXEL ON SYNTHESIZED CdS/NiO NANOPARTICLES AS PROMISING NANOCARRIERS
Objective: In this study cadmium sulfide (CdS) and nickel oxide (NiO) nanoparticles were synthesized and applied as novel nanocarriers for antibacterial drug clarithromycin (CLA) and anticancer drug paclitaxel (PTX) to i...