Abstract

Two types of extracts were prepared, methanolic and aqueous. Then, astandardphytochemical screening has been done to cast the light on its secondary metabolites. Also, biological activities were studied starting with the antioxidant activity using free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH), followed by an antidiabetic using the method of glucose uptake by yeast cells, last but not least the anti-proliferative activity on two types of cancer cells (Jurkat and MDA)using the neutral red assay. Obtained results revealed that seeds ofAnnona squamosa due to its content in some secondary metabolites such as flavonoids, phenol and alkaloids presentedan antioxidant capacity reaching a maximum of 61 % at the concentration 0.5 mg/mL for extracts, an antidiabetic property (96 %) at glucose concentration 10 mM and an anti-proliferative capacity. These results indicated that seeds could bea good source of element that may be used to help human health and to prevent some diseases.

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